OPENAIRE OpenAire ZENODO DOAJ Crossref Europe PubMed Central PubMed Central Sensors Open Access 2024-08-08 <?xml version='1.0' encoding='UTF-8'?><article><p>Molecularly imprinted membranes (MIMs) have been a focal research interest since 1990, representing a breakthrough in the integration of target molecules into membrane structures for cutting-edge sensing applications. This paper traces the developmental history of MIMs, elucidating the diverse methodologies employed in their preparation and characterization on two-dimensional solid-supported substrates. We then explore the principles and diverse applications of MIMs, particularly in the context of emerging technologies encompassing electrochemistry, surface-enhanced Raman scattering (SERS), surface plasmon resonance (SPR), and the quartz crystal microbalance (QCM). Furthermore, we shed light on the unique features of ion-sensitive field-effect transistor (ISFET) biosensors that rely on MIMs, with the notable advancements and challenges of point-of-care biochemical sensors highlighted. By providing a comprehensive overview of the latest innovations and future trajectories, this paper aims to inspire further exploration and progress in the field of MIM-driven sensing technologies.</p></article> point-of-care testing molecularly imprinted membranes ion-sensitive field-effect transistor Chemical technology biochemical sensors TP1-1185 Review 02 engineering and technology 0210 nano-technology all-solid-state 01 natural sciences 0104 chemical sciences Lishuang Wang, Nan Li, Xiaoyan Zhang, Ivan Bobrinetskiy, Ivana Gadjanski, Wangyang Fu, 2024-08-07 journalpaper <?xml version='1.0' encoding='UTF-8'?><article><p>Molecularly imprinted membranes (MIMs) have been a focal research interest since 1990, representing a breakthrough in the integration of target molecules into membrane structures for cutting-edge sensing applications. This paper traces the developmental history of MIMs, elucidating the diverse methodologies employed in their preparation and characterization on two-dimensional solid-supported substrates. We then explore the principles and diverse applications of MIMs, particularly in the context of emerging technologies encompassing electrochemistry, surface-enhanced Raman scattering (SERS), surface plasmon resonance (SPR), and the quartz crystal microbalance (QCM). Furthermore, we shed light on the unique features of ion-sensitive field-effect transistor (ISFET) biosensors that rely on MIMs, with the notable advancements and challenges of point-of-care biochemical sensors highlighted. By providing a comprehensive overview of the latest innovations and future trajectories, this paper aims to inspire further exploration and progress in the field of MIM-driven sensing technologies.</p></article> Sensing with Molecularly Imprinted Membranes on Two-Dimensional Solid-Supported Substrates 10.3390/s24165119 https://doi.org/10.3390/s24165119 739570