{"type": "FeatureCollection", "features": [{"id": "10.15454/2zqkir", "type": "Feature", "geometry": null, "properties": {"updated": "2026-07-25T16:19:41Z", "type": "Dataset", "title": "Science for policy 6: Urban planning: sealing the future of soil functions - datasets?", "description": "Open AccessThis dataset is part of Deliverable and 5.3 and produced by the WP4 team of the Landmark H2020 project. It contains the following shapefiles: PO6_BAU_NoZoning_50.shp PO6_BAU_NoZoning_100.shp PO6_BAU_Zoning_50.shp PO6_Sprawl_Zoning_50.shp PO6_BAU_NoZoning_50.shp PO6_Compact_Zoning_50.shp PO6_Compact_NoZoning_50.shp The metronamica Model was applied on six scenarios with combinations of business as usual, suburban sprawl or compact city development which build on the socio-economic projections and density assumptions of the ESPON-ET2050 project, and use the land use allocation parameters from the RECARE and SoilCare Integrated Assessment Models. Spatial development (zoning) was for some scenarios restricted in high productive fields. The model results give probabilities (0 \u2013 1) of urban development within the 1 km\u00b2 cells. Based on these probability percentages the different soil functions are reduced (100% of the probability and 50% of the probability) compared to the current soil functioning and, for the 50% scenarios, partly replaced by low productive grasslands as gardens and other public greenery. Z-scores are calculated from the spatial SF maps for each of the environmental zones. These environmental zones are derived from the Metzger et al. (2013). The z-scores give the signed fractional number of standard deviations by which SF means for an environmental zone are above or below the mean value and allow us indicate which areas have a higher or lower soil function performance compared to the mean value. Z-scores from the current SF maps and scenario maps were then compared to each other to calculate the change in z-scores. This change in z-scores is given in the shapefiles and describes the relative change in soil function performance. Positive values indicate an improvement in soil functioning compared to the current situation, negative values a decrease. More information regarding calculation and interpretation of both this dataset and the soil function maps used to calculate the z-scores can be found in: Vrebos D., F. Bampa, R. Creamer, A. Jones, E. Lugato, L. O\u2019Sullivan, P. Meire, R.P.O. Schulte, J. Schr\u00f6der and J. Staes (2018). Scenarios maps: visualizing optimized scenarios where supply of soil functions matches demands. LANDMARK Report 4.3. and Jones A. et al. (2019). An options document to propose future policy tools for functional soil management. LANDMARK 5.3. All available from www.landmark2020.eu.", "keywords": ["Water resources", "Food Safety", "Food Safety and Toxicology", "Nutritional Sciences", "Social Sciences", "7. Clean energy", "Pathology and Forensic Medicine", "Health and Life Sciences", "Farming Systems and Practices", "11. Sustainability", "13. Climate action", "Agriculture", " Forestry", " Horticulture", "Human Health and Pathology", "Soils and soil sciences", "Agricultural Sciences", "Life Sciences", "Hydrology and Hydrogeology", "15. Life on land", "Rural and Agricultural Sociology", "Human Nutrition and food security", "Farming Systems", "Medicine", " Health and Life Sciences", "Earth and Environmental Sciences", "Soil Sciences", "Medicine", "Geosciences"], "contacts": [{"organization": "Vrebos, Dirk, Bampa, Francesca, Schulte, Rogier, Creamer, Rachel, Jones, Arwyn, Staes, Jan, Zwetsloot Marie, Debernardini, Mariana, O\u2019Sullivan, Lilian,", "roles": ["creator"]}]}, "links": [{"href": "https://doi.org/10.15454/2zqkir"}, {"rel": "self", "type": "application/geo+json", "title": "10.15454/2zqkir", "name": "item", "description": "10.15454/2zqkir", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/10.15454/2zqkir"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2019-01-01T00:00:00Z"}}, {"id": "3114970092", "type": "Feature", "geometry": null, "properties": {"license": "Open Access", "updated": "2026-07-25T16:26:18Z", "type": "Dataset", "title": "Science for policy 6: Urban planning: sealing the future of soil functions - datasets?", "description": "Open AccessThis dataset is part of Deliverable and 5.3 and produced by the WP4 team of the Landmark H2020 project. It contains the following shapefiles: PO6_BAU_NoZoning_50.shp PO6_BAU_NoZoning_100.shp PO6_BAU_Zoning_50.shp PO6_Sprawl_Zoning_50.shp PO6_BAU_NoZoning_50.shp PO6_Compact_Zoning_50.shp PO6_Compact_NoZoning_50.shp The metronamica Model was applied on six scenarios with combinations of business as usual, suburban sprawl or compact city development which build on the socio-economic projections and density assumptions of the ESPON-ET2050 project, and use the land use allocation parameters from the RECARE and SoilCare Integrated Assessment Models. Spatial development (zoning) was for some scenarios restricted in high productive fields. The model results give probabilities (0 \u2013 1) of urban development within the 1 km\u00b2 cells. Based on these probability percentages the different soil functions are reduced (100% of the probability and 50% of the probability) compared to the current soil functioning and, for the 50% scenarios, partly replaced by low productive grasslands as gardens and other public greenery. Z-scores are calculated from the spatial SF maps for each of the environmental zones. These environmental zones are derived from the Metzger et al. (2013). The z-scores give the signed fractional number of standard deviations by which SF means for an environmental zone are above or below the mean value and allow us indicate which areas have a higher or lower soil function performance compared to the mean value. Z-scores from the current SF maps and scenario maps were then compared to each other to calculate the change in z-scores. This change in z-scores is given in the shapefiles and describes the relative change in soil function performance. Positive values indicate an improvement in soil functioning compared to the current situation, negative values a decrease. More information regarding calculation and interpretation of both this dataset and the soil function maps used to calculate the z-scores can be found in: Vrebos D., F. Bampa, R. Creamer, A. Jones, E. Lugato, L. O\u2019Sullivan, P. Meire, R.P.O. Schulte, J. Schr\u00f6der and J. Staes (2018). Scenarios maps: visualizing optimized scenarios where supply of soil functions matches demands. LANDMARK Report 4.3. and Jones A. et al. (2019). An options document to propose future policy tools for functional soil management. LANDMARK 5.3. All available from www.landmark2020.eu.", "keywords": ["Water resources", "Food Safety", "Food Safety and Toxicology", "Nutritional Sciences", "Social Sciences", "7. Clean energy", "Pathology and Forensic Medicine", "Health and Life Sciences", "Farming Systems and Practices", "11. Sustainability", "13. Climate action", "Agriculture", " Forestry", " Horticulture", "Human Health and Pathology", "Soils and soil sciences", "Agricultural Sciences", "Life Sciences", "Hydrology and Hydrogeology", "15. Life on land", "Rural and Agricultural Sociology", "Human Nutrition and food security", "Farming Systems", "Medicine", " Health and Life Sciences", "Earth and Environmental Sciences", "Soil Sciences", "Medicine", "Geosciences"], "contacts": [{"organization": "Vrebos, Dirk, Bampa, Francesca, Schulte, Rogier, Creamer, Rachel, Jones, Arwyn, Staes, Jan, Zwetsloot Marie, Debernardini, Mariana, O\u2019Sullivan, Lilian,", "roles": ["creator"]}]}, "links": [{"href": "https://doi.org/3114970092"}, {"rel": "self", "type": "application/geo+json", "title": "3114970092", "name": "item", "description": "3114970092", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/3114970092"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2019-01-01T00:00:00Z"}}, {"id": "1e653c62e5737fecd5d1bfcda54efca7", "type": "Feature", "geometry": null, "properties": {"license": "Open Access", "updated": "2026-07-25T16:25:25Z", "type": "Report", "title": "Noninvasive oxgenation strategies in immunocompromised patients with acute hypoxemic respiratory failure.", "description": "Open AccessL\u2019insuffisance respiratoire aigu\u00eb est la premi\u00e8re cause d\u2019admission en R\u00e9animation des patients immunod\u00e9prim\u00e9s. Malgr\u00e9 les progr\u00e8s th\u00e9rapeutiques, leur mortalit\u00e9 reste tr\u00e8s \u00e9lev\u00e9e en cas de recours \u00e0 la ventilation m\u00e9canique invasive. La ventilation non invasive (VNI) est recommand\u00e9e comme traitement de premi\u00e8re ligne en raison de la diminution de mortalit\u00e9 rapport\u00e9e dans les \u00e9tudes randomis\u00e9es anciennes. R\u00e9cemment, ces b\u00e9n\u00e9fices ont \u00e9t\u00e9 remis en cause par des essais de plus grande ampleur. Toutefois, il est possible que les r\u00e9glages de la VNI n\u2019aient pas \u00e9t\u00e9 optimaux dans ces \u00e9tudes, diminuant ainsi son efficacit\u00e9. Par ailleurs, l\u2019oxyg\u00e9noth\u00e9rapie nasale \u00e0 haut d\u00e9bit (OHD) est une technique d\u2019oxyg\u00e9nation r\u00e9cente avec des r\u00e9sultats prometteurs dans de nombreuses situations cliniques. L\u2019objectif final de ce projet \u00e9tait de conduire une \u00e9tude prospective randomis\u00e9e multicentrique comparant la VNI avec des r\u00e9glages optimis\u00e9s \u00e0 l\u2019OHD chez les patients immunod\u00e9prim\u00e9s admis en R\u00e9animation pour une insuffisance respiratoire aigu\u00eb. Nous avons tout d\u2019abord valid\u00e9 l\u2019hypoth\u00e8se de recherche du projet, son objectif principal, les calculs d\u2019effectif et le taux de recrutement au moyen d\u2019une \u00e9tude pilote r\u00e9trospective. Puis nous avons \u00e9labor\u00e9 le protocole de VNI \u00e0 partir d\u2019une revue syst\u00e9matique de la litt\u00e9rature comparant l\u2019efficacit\u00e9 des diff\u00e9rents protocoles de VNI publi\u00e9s. Ensuite, nous avons analys\u00e9 les facteurs de risque d\u2019\u00e9chec de la VNI chez les patients hypox\u00e9miques afin d\u2019identifier les param\u00e8tres physiologiques respiratoires \u00e0 surveiller chez les patients trait\u00e9s par VNI. En outre, nous avons identifi\u00e9 les m\u00e9canismes responsables des effets physiologiques de l\u2019OHD au moyen d\u2019une \u00e9tude sur banc puis chez des volontaires sains. Enfin, nous avons s\u00e9lectionn\u00e9 la m\u00e9thode d\u2019estimation de la fraction inspir\u00e9e en dioxyg\u00e8ne mesur\u00e9e au masque la plus fiable en comparant les diff\u00e9rentes m\u00e9thodes existantes dans le but d\u2019affiner les crit\u00e8res d\u2019inclusion du projet. Ces cinq \u00e9tudes pr\u00e9liminaires nous ont permis de conduire une \u00e9tude prospective randomis\u00e9e dans 30 centres en France et en Italie dans le but de comparer les effets de l\u2019OHD seule d\u00e9livr\u00e9e \u00e0 60 L/min \u00e0 son association \u00e0 la VNI intensive (administr\u00e9e au moins 12 heures par jour avec une pression expiratoire positive d\u2019au moins 8 cmH2O et un volume courant expir\u00e9 inf\u00e9rieur \u00e0 8 ml/kg de poids pr\u00e9dit) sur la mortalit\u00e9 \u00e0 28 jours chez 300 patients immunod\u00e9prim\u00e9s admis en R\u00e9animation pour une insuffisance respiratoire aigu\u00eb.", "keywords": ["Clinical study", "Immunod\u00e9pression", "[SDV.MHEP] Life Sciences [q-bio]/Human health and pathology", "High-Flow nasal cannula oxygen therapy", "Ventilation non invasive", "\u00c9tude clinique", "[SDV.MHEP.PSR] Life Sciences [q-bio]/Human health and pathology/Pulmonology and respiratory tract", "Insuffisance respiratoire aigu\u00eb", "Oxyg\u00e9noth\u00e9rapie nasale \u00e0 haut d\u00e9bit", "Acute respiratory failure", "Noninvasive ventilation", "Immunosuppression"], "contacts": [{"organization": "Coudroy, R\u00e9mi", "roles": ["creator"]}]}, "links": [{"href": "https://doi.org/1e653c62e5737fecd5d1bfcda54efca7"}, {"rel": "self", "type": "application/geo+json", "title": "1e653c62e5737fecd5d1bfcda54efca7", "name": "item", "description": "1e653c62e5737fecd5d1bfcda54efca7", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/1e653c62e5737fecd5d1bfcda54efca7"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2019-01-01T00:00:00Z"}}, {"id": "a7e3fe76872a58bceb6ba68fea80dda3", "type": "Feature", "geometry": null, "properties": {"license": "Open Access", "updated": "2026-07-25T16:28:42Z", "type": "Report", "title": "The AGE-breaker ALT-711 restores high blood flow-dependent remodeling in mesenteric resistance arteries in a rat model of type 2 diabetes.", "description": "Flow-mediated remodeling of resistance arteries is essential for revascularization in ischemic diseases, but this is impaired in diabetes. We hypothesized that breaking advanced glycation end product (AGE) cross-links could improve remodeling in mesenteric resistance arteries in Zucker diabetic fatty (ZDF) rats compared with lean Zucker (LZ) rats. Arteries, exposed to high (HF) or normal (NF) blood flow after alternate arterial ligation in vivo, were collected after 2 weeks. In LZ rats, HF artery diameter was larger than for NF vessels, but this was not the case in ZDF rats. Endothelium-mediated dilation in ZDF rats, which was lower than in LZ rats, was further decreased in HF arteries. Treatment of rats with the AGE-breaker 4,5-dimethyl-3-phenacylthiazolium chloride (ALT-711) (3 mg/kg/day; 3 weeks) reversed diabetes-induced impairment of HF-dependent remodeling. ALT-711 also improved endothelium nitric oxide-dependent relaxation in mesenteric resistance arteries. Reactive oxygen species reduction restored relaxation in ZDF rats but not in LZ or ALT-711-treated rats. AGEs were reduced in ALT-711-treated ZDF rats compared with ZDF rats. Metalloproteinase activity, necessary for HF-dependent remodeling, was reduced in ZDF rats compared with LZ rats and restored by ALT-711. Thus, targeting AGE cross-links may provide a therapeutic potential for overcoming microvascular complications in ischemic disorders occurring in diabetes.", "keywords": ["[SDV.MHEP.CSC] Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system"], "contacts": [{"organization": "Freidja, Mohamed, Tarhouni, Kahena, Toutain, Bertrand, Fassot, C\u00e9line, Loufrani, Laurent, Henrion, Daniel,", "roles": ["creator"]}]}, "links": [{"href": "https://doi.org/a7e3fe76872a58bceb6ba68fea80dda3"}, {"rel": "self", "type": "application/geo+json", "title": "a7e3fe76872a58bceb6ba68fea80dda3", "name": "item", "description": "a7e3fe76872a58bceb6ba68fea80dda3", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/a7e3fe76872a58bceb6ba68fea80dda3"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2012-01-01T00:00:00Z"}}, {"id": "aac6ae47d0f5fcd32e3687c113d7560c", "type": "Feature", "geometry": null, "properties": {"license": "Open Access", "updated": "2026-07-25T16:28:44Z", "type": "Report", "title": "Breech presentation: Clinical practice guidelines from the French College of Gynaecologists and Obstetricians (CNGOF)", "description": "Objective: To determine the optimal management of singleton fetuses in breech presentation. Materials and methods: Consultation of the PubMed database, the Cochrane Library and guidelines issued by the French and foreign obstetrical societies or colleges. Results: In France, 5% of women have breech deliveries (level of evidence [LE] 3). One third of them have a planned vaginal delivery (LE3), and 70% of these give birth vaginally (LE3). External cephalic version (ECV) is associated with lower rates of both breech presentation at birth (LE2) and of cesarean deliveries (LE3) without any increase in severe maternal (LE3) or perinatal morbidity (LE3). Women with a fetus in breech presentation at term should be informed that ECV can be attempted starting at 36 weeks of gestation (professional consensus). Planned vaginal delivery of breech presentation may be associated with a higher risk of composite perinatal mortality or serious neonatal morbidity than planned cesarean birth (LE2). These two modes do not differ for neurodevelopmental outcomes at two years (LE2), cognitive and psychomotor outcomes between 5 and 8 years (LE3), or adult intellectual performance (LE4). Short- and long-term maternal complications appear similar in the two groups, unless subsequent pregnancies are under consideration. Pregnancies after a cesarean delivery are at higher risk of uterine rupture, placenta accreta spectrum disorders, and hysterectomy (LE2). Women who want a planned vaginal delivery should be offered a pelvimetry at term (Grade C) and should have ultrasonography to verify that the fetal head is not hyperextended (professional consensus) to plan their mode of delivery. Complete breech presentation, a previous cesarean, nulliparity, and term prelabor rupture of membranes are not, each one by itself, per se contraindications to planned vaginal delivery (professional consensus). Term breech presentation is not a contraindication to labor induction when the criteria for planned vaginal delivery are met (Grade C). Conclusion: In cases of breech presentation at term, the child and the mother are at low risk of severe morbidity after either planned vaginal or planned cesarean delivery. The French College of Obstetricians and Gynecologists (CNGOF) considers that planned vaginal delivery is a reasonable option in most cases (professional consensus). The decision about the planned route of delivery should be shared by the woman and her healthcare provider, who must respect her right to autonomy.", "keywords": ["[SDV.MHEP.GEO] Life Sciences [q-bio]/Human health and pathology/Gynecology and obstetrics", "External cephalic version", "Breech presentation", "Trial of labor", "Maternal and neonatal morbidity", "Planned cesarean delivery", "Planned vaginal delivery"], "contacts": [{"organization": "Sentilhes, L\u00f6ic, Schmitz, Thomas, Azria, \u00c9lie, Gallot, Dennis, Ducarme, Guillaume, Korb, Diane, Mattuizzi, Aur\u00e9lien, Parant, Olivier, Sanan\u00e8s, Nicolas, Baumann, Sophie, Rozenberg, Patrick, S\u00e9nat, Marie Victoire, Verspyck, \u00c9ric,", "roles": ["creator"]}]}, "links": [{"href": "https://doi.org/aac6ae47d0f5fcd32e3687c113d7560c"}, {"rel": "self", "type": "application/geo+json", "title": "aac6ae47d0f5fcd32e3687c113d7560c", "name": "item", "description": "aac6ae47d0f5fcd32e3687c113d7560c", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/aac6ae47d0f5fcd32e3687c113d7560c"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2020-01-01T00:00:00Z"}}], "links": [{"rel": "self", "type": "application/geo+json", "title": "This document as GeoJSON", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items?keywords=Human+Health+and+Pathology&f=json", "hreflang": "en-US"}, {"rel": "alternate", "type": "text/html", "title": "This document as HTML", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items?keywords=Human+Health+and+Pathology&f=html", "hreflang": "en-US"}, {"rel": "collection", "type": "application/json", "title": "Collection URL", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main", "hreflang": "en-US"}, {"type": "application/geo+json", "rel": "first", "title": "items (first)", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items?keywords=Human+Health+and+Pathology&", "hreflang": "en-US"}, {"rel": "last", "type": "application/geo+json", "title": "items (last)", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items?keywords=Human+Health+and+Pathology&offset=5", "hreflang": "en-US"}], "numberMatched": 5, "numberReturned": 5, "distributedFeatures": [], "timeStamp": "2026-07-25T23:38:34.018365Z"}