{"type": "FeatureCollection", "features": [{"id": "10.1038/s41598-022-24124-6", "type": "Feature", "geometry": null, "properties": {"updated": "2026-07-27T16:18:26Z", "type": "Journal Article", "created": "2022-11-15", "title": "Microfluidic study in a meter-long reactive path reveals how the medium\u2019s structural heterogeneity shapes MICP-induced biocementation", "description": "Abstract

Microbially induced calcium carbonate (CaCO3) precipitation (MICP) is one of the major sustainable alternatives to the artificial cementation of granular media. MICP consists of injecting the soil with bacterial- and calcium-rich solutions sequentially to form calcite bonds among the soil particles that improve the strength and stiffness of soils. The performance of MICP is governed by the underlying microscale processes of bacterial growth, reactive transport of solutes, reaction rates, crystal nucleation and growth. However, the impact of pore-scale heterogeneity on these processes during MICP is not well understood. This paper sheds light on the effect of pore-scale heterogeneity on the spatiotemporal evolution of MICP, overall chemical reaction efficiency and permeability evolution by combining two meter-long microfluidic devices of identical dimensions and porosity with homogeneous and heterogeneous porous networks and real-time monitoring. The two chips received, in triplicate, MICP treatment with an imposed flow and the same initial conditions, while the inlet and outlet pressures were periodically monitored. This paper proposes a comprehensive workflow destined to detect bacteria and crystals from time-lapse microscopy data at multiple positions along a microfluidic replica of porous media treated with MICP. CaCO3 crystals were formed 1\uffc2\uffa0h after the introduction of the cementation solution (CS), and crystal growth was completed 12\uffc2\uffa0h later. The average crystal growth rate was overall higher in the heterogeneous porous medium, while it became slower after the first 3\uffc2\uffa0h of cementation injection. It was found that the average chemical reaction efficiency presented a peak of 34% at the middle of the chip and remained above 20% before the last 90\uffc2\uffa0mm of the reactive path for the heterogeneous porous network. The homogeneous porous medium presented an overall lower average reaction efficiency, which peaked at 27% 420\uffc2\uffa0mm downstream of the inlet and remained lower than 12% for the rest of the microfluidic channel. These different trends of chemical efficiency in the two networks are due to a higher number of crystals of higher average diameter in the heterogeneous medium than in the homogeneous porous medium. In the interval between 480 and 900\uffc2\uffa0mm, the number of crystals in the heterogeneous porous medium is more than double the number of crystals in the homogeneous porous medium. The average diameters of the crystals were 23\uffe2\uff80\uff9346\uffc2\uffa0\uffce\uffbcm in the heterogeneous porous medium, compared to 17\uffe2\uff80\uff9340\uffc2\uffa0\uffce\uffbcm in the homogeneous porous medium across the whole chip. The permeability of the heterogeneous porous medium was more affected than that of the homogeneous system, while the pressure sensors effectively captured a higher decrease in the permeability during the first two hours when crystals were formed and a less prominent decrease during the subsequent seeded growth of the existing crystals, as well as the nucleation and growth of new crystals.

Droplet-based microfluidics has revolutionized numerous fields such as biomedical research, pharmaceuticals, drug discovery, food engineering, flow chemistry, and cosmetics. This paper presents a comprehensive study focusing on the detection and characterization of droplets with volumes in the nanoliter range. Leveraging the precise control of minute liquid volumes, we introduced a novel spectroscopic On-Chip microsensor equipped with integrated microfluidic channels for droplet generation, characterization, and sensing, simultaneously. The microsensor, designed with Interdigitated-Ring-Shaped Electrodes (IRSE) and seamlessly integrated with microfluidic channels, offers enhanced capacitance and impedance signal amplitudes, reproducibility, and reliability in droplet analysis. We were able to make analyses of droplets length in the range 1.0-6.0 mm, velocity 0.66-2.51 mm/s, droplet volume 1.07nL-113.46nL. Experimental results demonstrated that the microsensor's has a great performance in terms of droplet size, velocity, and length, with a significant signal amplitude of capacitance and impedance, and real-time detection capabilities, thereby highlighting its potential for facilitating microcapsule reactions and enabling on-site real-time detection for chemical and biosensor analyses on-chip.

", "keywords": ["0301 basic medicine", "lab-on-a-chip sensor", "03 medical and health sciences", "spectroscopic sensing", "droplet-based microfluidics", "TJ1-1570", "real-time", "microfluidics device", "Mechanical engineering and machinery", "interdigitated electrode", "01 natural sciences", "Article", "0104 chemical sciences"]}, "links": [{"href": "https://doi.org/10.20944/preprints202404.0289.v1"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/Micromachines", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "10.20944/preprints202404.0289.v1", "name": "item", "description": "10.20944/preprints202404.0289.v1", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/10.20944/preprints202404.0289.v1"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2024-04-03T00:00:00Z"}}, {"id": "10.3390/pr9081320", "type": "Feature", "geometry": null, "properties": {"license": "Open Access", "updated": "2026-07-27T16:21:57Z", "type": "Journal Article", "created": "2021-07-29", "title": "Microfluidic Network Simulations Enable On-Demand Prediction of Control Parameters for Operating Lab-on-a-Chip-Devices", "description": "

Reliable operation of lab-on-a-chip systems depends on user-friendly, precise, and predictable fluid management tailored to particular sub-tasks of the microfluidic process protocol and their required sample fluids. Pressure-driven flow control, where the sample fluids are delivered to the chip from pressurized feed vessels, simplifies the fluid management even for multiple fluids. The achieved flow rates depend on the pressure settings, fluid properties, and pressure-throughput characteristics of the complete microfluidic system composed of the chip and the interconnecting tubing. The prediction of the required pressure settings for achieving given flow rates simplifies the control tasks and enables opportunities for automation. In our work, we utilize a fast-running, Kirchhoff-based microfluidic network simulation that solves the complete microfluidic system for in-line prediction of the required pressure settings within less than 200 ms. The appropriateness of and benefits from this approach are demonstrated as exemplary for creating multi-component laminar co-flow and the creation of droplets with variable composition. Image-based methods were combined with chemometric approaches for the readout and correlation of the created multi-component flow patterns with the predictions obtained from the solver.

", "keywords": ["droplet microfluidics", "laminar flow", "microfluidic network solver", "9. Industry and infrastructure", "Kirchhoff-solver", "microfluidics", "chemometric analysis", "02 engineering and technology", "microfluidic design automation", "0210 nano-technology", "pressure-driven flow-control", "6. Clean water", "lab-on-a-chip simulation"]}, "links": [{"href": "http://www.mdpi.com/2227-9717/9/8/1320/pdf"}, {"href": "https://www.mdpi.com/2227-9717/9/8/1320/pdf"}, {"href": "https://doi.org/10.3390/pr9081320"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/Processes", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "10.3390/pr9081320", "name": "item", "description": "10.3390/pr9081320", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/10.3390/pr9081320"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2021-07-29T00:00:00Z"}}, {"id": "10.3390/s17040892", "type": "Feature", "geometry": null, "properties": {"updated": "2026-07-27T16:22:01Z", "type": "Journal Article", "created": "2017-04-18", "title": "Microfluidic EBG Sensor Based on Phase-Shift Method Realized Using 3D Printing Technology", "description": "

In this article, we propose a novel microfluidic microstrip electromagnetic band gap (EBG) sensor realized using cost-effective 3D printing technology. Microstrip sensor allows monitoring of the fluid properties flowing in the microchannel embedded between the microstrip line and ground plane. The sensor\u2019s operating principle is based on the phase-shift method, which allows the characterization at a single operating frequency of 6 GHz. The defected electromagnetic band gap (EBG) structure is realized as a pattern in the microstrip ground plane to improve sensor sensitivity. The designed microfluidic channel is fabricated using a fused deposition modelling (FDM) 3D printing process without additional supporting layers, while the conductive layers are realized using sticky aluminium tape. The measurement results show that the change of permittivity of the fluid in the microfluidic channel from 1 to 80 results in the phase-shift difference of almost 90\u00b0. The potential application is demonstrated through the implementation of a proposed sensor for the detection of toluene concentration in toluene\u2013methanol mixture where various concentrations of toluene were analysed.

", "keywords": ["fused deposition modelling (FDM)", "electromagnetic band gap (EBG)", "Chemical technology", "microfluidics", "phase-shift method", "0202 electrical engineering", " electronic engineering", " information engineering", "microstrip sensor; electromagnetic band gap (EBG); microfluidics; 3D printing; fused deposition modelling (FDM); phase-shift method", "microstrip sensor", "3D printing", "TP1-1185", "02 engineering and technology", "Article"]}, "links": [{"href": "http://www.mdpi.com/1424-8220/17/4/892/pdf"}, {"href": "https://doi.org/10.3390/s17040892"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/Sensors", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "10.3390/s17040892", "name": "item", "description": "10.3390/s17040892", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/10.3390/s17040892"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2017-04-18T00:00:00Z"}}, {"id": "10.3390/s17122713", "type": "Feature", "geometry": null, "properties": {"updated": "2026-07-27T16:22:01Z", "type": "Journal Article", "created": "2017-11-24", "title": "A Microwave Microfluidic Sensor Based on a Dual-Mode Resonator for Dual-Sensing Applications", "description": "

In this paper, we propose a novel microwave microfluidic sensor with dual-sensing capability. The sensor is based on a dual-mode resonator that consists of a folded microstrip line loaded with interdigital lines and a stub at the plane of symmetry. Due to the specific configuration, the resonator exhibits two entirely independent resonant modes, which allows simultaneous sensing of two fluids using a resonance shift method. The sensor is designed in a multilayer configuration with the proposed resonator and two separated microfluidic channels\uffe2\uff80\uff94one intertwined with the interdigital lines and the other positioned below the stub. The circuit has been fabricated using low-temperature co-fired ceramics technology and its performance was verified through the measurement of its responses for different fluids in the microfluidic channels. The results confirm the dual-sensing capability with zero mutual influence as well as good overall performance. Besides an excellent potential for dual-sensing applications, the proposed sensor is a good candidate for application in mixing fluids and cell counting.

", "keywords": ["dual-mode resonator", "Chemical technology", "microwave sensor", "microfluidics", "TP1-1185", "02 engineering and technology", "low-temperature co-fired ceramics", "7. Clean energy", "01 natural sciences", "Article", "0104 chemical sciences", "microwave sensor; dual-mode resonator; microstrip; microfluidics; low-temperature co-fired ceramics", "0202 electrical engineering", " electronic engineering", " information engineering", "microstrip"]}, "links": [{"href": "http://www.mdpi.com/1424-8220/17/12/2713/pdf"}, {"href": "https://www.mdpi.com/1424-8220/17/12/2713/pdf"}, {"href": "https://doi.org/10.3390/s17122713"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/Sensors", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "10.3390/s17122713", "name": "item", "description": "10.3390/s17122713", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/10.3390/s17122713"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2017-11-24T00:00:00Z"}}, {"id": "10.3390/s18072250", "type": "Feature", "geometry": null, "properties": {"license": "Open Access", "updated": "2026-07-27T16:22:01Z", "type": "Journal Article", "created": "2018-07-12", "title": "Biosensing System for Concentration Quantification of Magnetically Labeled E. coli in Water Samples", "description": "

Bacterial contamination of water sources (e.g., lakes, rivers and springs) from waterborne bacteria is a crucial water safety issue and its prevention is of the utmost significance since it threatens the health and well-being of wildlife, livestock, and human populations and can lead to serious illness and even death. Rapid and multiplexed measurement of such waterborne pathogens is vital and the challenge is to instantly detect in these liquid samples different types of pathogens with high sensitivity and specificity. In this work, we propose a biosensing system in which the bacteria are labelled with streptavidin coated magnetic markers (MPs\u2014magnetic particles) forming compounds (MLBs\u2014magnetically labelled bacteria). Video microscopy in combination with a particle tracking software are used for their detection and quantification. When the liquid containing the MLBs is introduced into the developed, microfluidic platform, the MLBs are accelerated towards the outlet by means of a magnetic field gradient generated by integrated microconductors, which are sequentially switched ON and OFF by a microcontroller. The velocities of the MLBs and that of reference MPs, suspended in the same liquid in a parallel reference microfluidic channel, are calculated and compared in real time by a digital camera mounted on a conventional optical microscope in combination with a particle trajectory tracking software. The MLBs will be slower than the reference MPs due to the enhanced Stokes\u2019 drag force exerted on them, resulting from their greater volume and altered hydrodynamic shape. The results of the investigation showed that the parameters obtained from this method emerged as reliable predictors for E. coli concentrations.

", "keywords": ["0301 basic medicine", "0303 health sciences", "magnetophoresis", "magnetic microparticles", "Chemical technology", "magnetic labeling", "Microfluidics", "TP1-1185", "Biosensing Techniques", "Article", "6. Clean water", "particle tracking", "Magnetics", "03 medical and health sciences", "bacteria quantification", "13. Climate action", "Escherichia coli", "biosensing", "Water Microbiology"]}, "links": [{"href": "http://www.mdpi.com/1424-8220/18/7/2250/pdf"}, {"href": "https://doi.org/10.3390/s18072250"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/Sensors", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "10.3390/s18072250", "name": "item", "description": "10.3390/s18072250", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/10.3390/s18072250"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2018-07-12T00:00:00Z"}}, {"id": "2768681626", "type": "Feature", "geometry": null, "properties": {"updated": "2026-07-27T16:27:11Z", "type": "Journal Article", "created": "2017-11-24", "title": "A Microwave Microfluidic Sensor Based on a Dual-Mode Resonator for Dual-Sensing Applications", "description": "

In this paper, we propose a novel microwave microfluidic sensor with dual-sensing capability. The sensor is based on a dual-mode resonator that consists of a folded microstrip line loaded with interdigital lines and a stub at the plane of symmetry. Due to the specific configuration, the resonator exhibits two entirely independent resonant modes, which allows simultaneous sensing of two fluids using a resonance shift method. The sensor is designed in a multilayer configuration with the proposed resonator and two separated microfluidic channels\u2014one intertwined with the interdigital lines and the other positioned below the stub. The circuit has been fabricated using low-temperature co-fired ceramics technology and its performance was verified through the measurement of its responses for different fluids in the microfluidic channels. The results confirm the dual-sensing capability with zero mutual influence as well as good overall performance. Besides an excellent potential for dual-sensing applications, the proposed sensor is a good candidate for application in mixing fluids and cell counting.

", "keywords": ["dual-mode resonator", "Chemical technology", "microwave sensor", "microfluidics", "TP1-1185", "02 engineering and technology", "low-temperature co-fired ceramics", "7. Clean energy", "01 natural sciences", "Article", "0104 chemical sciences", "microwave sensor; dual-mode resonator; microstrip; microfluidics; low-temperature co-fired ceramics", "0202 electrical engineering", " electronic engineering", " information engineering", "microstrip"]}, "links": [{"href": "http://www.mdpi.com/1424-8220/17/12/2713/pdf"}, {"href": "https://www.mdpi.com/1424-8220/17/12/2713/pdf"}, {"href": "https://doi.org/2768681626"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/Sensors", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "2768681626", "name": "item", "description": "2768681626", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/2768681626"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2017-11-24T00:00:00Z"}}, {"id": "2607489812", "type": "Feature", "geometry": null, "properties": {"license": "Open Access", "updated": "2026-07-27T16:27:09Z", "type": "Journal Article", "created": "2017-04-18", "title": "Microfluidic EBG Sensor Based on Phase-Shift Method Realized Using 3D Printing Technology", "description": "

In this article, we propose a novel microfluidic microstrip electromagnetic band gap (EBG) sensor realized using cost-effective 3D printing technology. Microstrip sensor allows monitoring of the fluid properties flowing in the microchannel embedded between the microstrip line and ground plane. The sensor\u2019s operating principle is based on the phase-shift method, which allows the characterization at a single operating frequency of 6 GHz. The defected electromagnetic band gap (EBG) structure is realized as a pattern in the microstrip ground plane to improve sensor sensitivity. The designed microfluidic channel is fabricated using a fused deposition modelling (FDM) 3D printing process without additional supporting layers, while the conductive layers are realized using sticky aluminium tape. The measurement results show that the change of permittivity of the fluid in the microfluidic channel from 1 to 80 results in the phase-shift difference of almost 90\u00b0. The potential application is demonstrated through the implementation of a proposed sensor for the detection of toluene concentration in toluene\u2013methanol mixture where various concentrations of toluene were analysed.

", "keywords": ["fused deposition modelling (FDM)", "electromagnetic band gap (EBG)", "Chemical technology", "microfluidics", "phase-shift method", "0202 electrical engineering", " electronic engineering", " information engineering", "microstrip sensor; electromagnetic band gap (EBG); microfluidics; 3D printing; fused deposition modelling (FDM); phase-shift method", "microstrip sensor", "3D printing", "TP1-1185", "02 engineering and technology", "Article"]}, "links": [{"href": "http://www.mdpi.com/1424-8220/17/4/892/pdf"}, {"href": "https://doi.org/2607489812"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/Sensors", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "2607489812", "name": "item", "description": "2607489812", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/2607489812"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2017-04-18T00:00:00Z"}}, {"id": "2867552234", "type": "Feature", "geometry": null, "properties": {"license": "Open Access", "updated": "2026-07-27T16:27:14Z", "type": "Journal Article", "created": "2018-07-12", "title": "Biosensing System for Concentration Quantification of Magnetically Labeled E. coli in Water Samples", "description": "

Bacterial contamination of water sources (e.g., lakes, rivers and springs) from waterborne bacteria is a crucial water safety issue and its prevention is of the utmost significance since it threatens the health and well-being of wildlife, livestock, and human populations and can lead to serious illness and even death. Rapid and multiplexed measurement of such waterborne pathogens is vital and the challenge is to instantly detect in these liquid samples different types of pathogens with high sensitivity and specificity. In this work, we propose a biosensing system in which the bacteria are labelled with streptavidin coated magnetic markers (MPs\u2014magnetic particles) forming compounds (MLBs\u2014magnetically labelled bacteria). Video microscopy in combination with a particle tracking software are used for their detection and quantification. When the liquid containing the MLBs is introduced into the developed, microfluidic platform, the MLBs are accelerated towards the outlet by means of a magnetic field gradient generated by integrated microconductors, which are sequentially switched ON and OFF by a microcontroller. The velocities of the MLBs and that of reference MPs, suspended in the same liquid in a parallel reference microfluidic channel, are calculated and compared in real time by a digital camera mounted on a conventional optical microscope in combination with a particle trajectory tracking software. The MLBs will be slower than the reference MPs due to the enhanced Stokes\u2019 drag force exerted on them, resulting from their greater volume and altered hydrodynamic shape. The results of the investigation showed that the parameters obtained from this method emerged as reliable predictors for E. coli concentrations.

", "keywords": ["0301 basic medicine", "0303 health sciences", "magnetophoresis", "magnetic microparticles", "Chemical technology", "magnetic labeling", "Microfluidics", "TP1-1185", "Biosensing Techniques", "Article", "6. Clean water", "particle tracking", "Magnetics", "03 medical and health sciences", "bacteria quantification", "13. Climate action", "Escherichia coli", "biosensing", "Water Microbiology"]}, "links": [{"href": "http://www.mdpi.com/1424-8220/18/7/2250/pdf"}, {"href": "https://doi.org/2867552234"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/Sensors", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "2867552234", "name": "item", "description": "2867552234", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/2867552234"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2018-07-12T00:00:00Z"}}, {"id": "3186907671", "type": "Feature", "geometry": null, "properties": {"license": "Open Access", "updated": "2026-07-27T16:27:42Z", "type": "Journal Article", "created": "2021-07-30", "title": "Microfluidic Network Simulations Enable On-Demand Prediction of Control Parameters for Operating Lab-on-a-Chip-Devices", "description": "

Reliable operation of lab-on-a-chip systems depends on user-friendly, precise, and predictable fluid management tailored to particular sub-tasks of the microfluidic process protocol and their required sample fluids. Pressure-driven flow control, where the sample fluids are delivered to the chip from pressurized feed vessels, simplifies the fluid management even for multiple fluids. The achieved flow rates depend on the pressure settings, fluid properties, and pressure-throughput characteristics of the complete microfluidic system composed of the chip and the interconnecting tubing. The prediction of the required pressure settings for achieving given flow rates simplifies the control tasks and enables opportunities for automation. In our work, we utilize a fast-running, Kirchhoff-based microfluidic network simulation that solves the complete microfluidic system for in-line prediction of the required pressure settings within less than 200 ms. The appropriateness of and benefits from this approach are demonstrated as exemplary for creating multi-component laminar co-flow and the creation of droplets with variable composition. Image-based methods were combined with chemometric approaches for the readout and correlation of the created multi-component flow patterns with the predictions obtained from the solver.

", "keywords": ["droplet microfluidics", "laminar flow", "microfluidic network solver", "9. Industry and infrastructure", "Kirchhoff-solver", "microfluidics", "chemometric analysis", "02 engineering and technology", "microfluidic design automation", "0210 nano-technology", "pressure-driven flow-control", "6. Clean water", "lab-on-a-chip simulation"]}, "links": [{"href": "http://www.mdpi.com/2227-9717/9/8/1320/pdf"}, {"href": "https://www.mdpi.com/2227-9717/9/8/1320/pdf"}, {"href": "https://doi.org/3186907671"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/Processes", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "3186907671", "name": "item", "description": "3186907671", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/3186907671"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2021-07-29T00:00:00Z"}}, {"id": "50|od______2659::75ce3208bbf8bd77cc60507730caaff3", "type": "Feature", "geometry": null, "properties": {"license": "Open Access", "updated": "2026-07-27T16:28:21Z", "type": "Dataset", "title": "Microfluidic study in a meter-long reactive path reveals how the medium's structural heterogeneity shapes MICP-induced biocementation", "description": "This folder includes processed images and image analysis algorithm for the publication 'Microfluidic study in a meter-long reactive path reveals how the medium\u2019s structural heterogeneity shapes MICP-induced biocementation'. Each folder contains the results of image processing OBJ. Color explanation white: pore fluid, blue: bacteria, red: crystals, black: solid Numbering xy shows the id number of position t shows the id number of the time point Metadata Metadata extracted from microscopes during image acquisitions are provided in.txt format \u00a0 a .txt file is included showing the time of image acquisition in the first column the excel file shows the distance from injection point where images were captured", "keywords": ["microfluidics", " Microbially Induced Calcite Precipitation", " MICP", " image processing", " structural heterogeneity"], "contacts": [{"organization": "Ariadni Elmaloglou, Dimitrios Terzis, Pietro De Anna, Lyesse Laloui,", "roles": ["creator"]}]}, "links": [{"href": "https://doi.org/50|od______2659::75ce3208bbf8bd77cc60507730caaff3"}, {"rel": "self", "type": "application/geo+json", "title": "50|od______2659::75ce3208bbf8bd77cc60507730caaff3", "name": "item", "description": "50|od______2659::75ce3208bbf8bd77cc60507730caaff3", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/50|od______2659::75ce3208bbf8bd77cc60507730caaff3"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2023-01-07T00:00:00Z"}}, {"id": "50|od______2659::800b05ba312a905fd45a3767b555ffe1", "type": "Feature", "geometry": null, "properties": {"license": "Open Access", "updated": "2026-07-27T16:28:22Z", "type": "Dataset", "title": "Microfluidic study in a meter-long reactive path reveals how the medium's structural heterogeneity shapes MICP-induced biocementation", "description": "This folder includes processed images and image analysis algorithm for the publication 'Microfluidic study in a meter-long reactive path reveals how the medium\u2019s structural heterogeneity shapes MICP-induced biocementation'. Each folder contains the results of image processing OBJ. Color explanation white: pore fluid, blue: bacteria, red: crystals, black: solid Numbering xy shows the id number of position t shows the id number of the time point Metadata Metadata extracted from microscopes during image acquisitions are provided in.txt format \u00a0 a .txt file is included showing the time of image acquisition in the first column the excel file shows the distance from injection point where images were captured", "keywords": ["microfluidics", " Microbially Induced Calcite Precipitation", " MICP", " image processing", " structural heterogeneity"], "contacts": [{"organization": "Ariadni Elmaloglou, Dimitrios Terzis, Pietro De Anna, Lyesse Laloui,", "roles": ["creator"]}]}, "links": [{"href": "https://doi.org/50|od______2659::800b05ba312a905fd45a3767b555ffe1"}, {"rel": "self", "type": "application/geo+json", "title": "50|od______2659::800b05ba312a905fd45a3767b555ffe1", "name": "item", "description": "50|od______2659::800b05ba312a905fd45a3767b555ffe1", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/50|od______2659::800b05ba312a905fd45a3767b555ffe1"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2023-01-07T00:00:00Z"}}, {"id": "PMC11205656", "type": "Feature", "geometry": null, "properties": {"license": "Open Access", "updated": "2026-07-27T16:30:20Z", "type": "Journal Article", "created": "2024-04-04", "title": "A Novel Microfluidics Droplet-Based Interdigitated Ring-Shaped Electrode Sensor for Lab-on-a-Chip Applications", "description": "

Droplet-based microfluidics has revolutionized numerous fields such as biomedical research, pharmaceuticals, drug discovery, food engineering, flow chemistry, and cosmetics. This paper presents a comprehensive study focusing on the detection and characterization of droplets with volumes in the nanoliter range. Leveraging the precise control of minute liquid volumes, we introduced a novel spectroscopic On-Chip microsensor equipped with integrated microfluidic channels for droplet generation, characterization, and sensing, simultaneously. The microsensor, designed with Interdigitated-Ring-Shaped Electrodes (IRSE) and seamlessly integrated with microfluidic channels, offers enhanced capacitance and impedance signal amplitudes, reproducibility, and reliability in droplet analysis. We were able to make analyses of droplets length in the range 1.0-6.0 mm, velocity 0.66-2.51 mm/s, droplet volume 1.07nL-113.46nL. Experimental results demonstrated that the microsensor's has a great performance in terms of droplet size, velocity, and length, with a significant signal amplitude of capacitance and impedance, and real-time detection capabilities, thereby highlighting its potential for facilitating microcapsule reactions and enabling on-site real-time detection for chemical and biosensor analyses on-chip.

", "keywords": ["0301 basic medicine", "lab-on-a-chip sensor", "03 medical and health sciences", "spectroscopic sensing", "droplet-based microfluidics", "TJ1-1570", "real-time", "microfluidics device", "Mechanical engineering and machinery", "interdigitated electrode", "01 natural sciences", "Article", "0104 chemical sciences"]}, "links": [{"href": "https://doi.org/PMC11205656"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/Micromachines", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "PMC11205656", "name": "item", "description": "PMC11205656", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/PMC11205656"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2024-04-03T00:00:00Z"}}, {"id": "PMC5426542", "type": "Feature", "geometry": null, "properties": {"updated": "2026-07-27T16:30:24Z", "type": "Journal Article", "created": "2017-04-18", "title": "Microfluidic EBG Sensor Based on Phase-Shift Method Realized Using 3D Printing Technology", "description": "

In this article, we propose a novel microfluidic microstrip electromagnetic band gap (EBG) sensor realized using cost-effective 3D printing technology. Microstrip sensor allows monitoring of the fluid properties flowing in the microchannel embedded between the microstrip line and ground plane. The sensor\u2019s operating principle is based on the phase-shift method, which allows the characterization at a single operating frequency of 6 GHz. The defected electromagnetic band gap (EBG) structure is realized as a pattern in the microstrip ground plane to improve sensor sensitivity. The designed microfluidic channel is fabricated using a fused deposition modelling (FDM) 3D printing process without additional supporting layers, while the conductive layers are realized using sticky aluminium tape. The measurement results show that the change of permittivity of the fluid in the microfluidic channel from 1 to 80 results in the phase-shift difference of almost 90\u00b0. The potential application is demonstrated through the implementation of a proposed sensor for the detection of toluene concentration in toluene\u2013methanol mixture where various concentrations of toluene were analysed.

", "keywords": ["fused deposition modelling (FDM)", "electromagnetic band gap (EBG)", "Chemical technology", "microfluidics", "phase-shift method", "0202 electrical engineering", " electronic engineering", " information engineering", "microstrip sensor; electromagnetic band gap (EBG); microfluidics; 3D printing; fused deposition modelling (FDM); phase-shift method", "microstrip sensor", "3D printing", "TP1-1185", "02 engineering and technology", "Article"]}, "links": [{"href": "http://www.mdpi.com/1424-8220/17/4/892/pdf"}, {"href": "https://doi.org/PMC5426542"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/Sensors", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "PMC5426542", "name": "item", "description": "PMC5426542", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/PMC5426542"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2017-04-18T00:00:00Z"}}, {"id": "PMC5750723", "type": "Feature", "geometry": null, "properties": {"updated": "2026-07-27T16:30:25Z", "type": "Journal Article", "created": "2017-11-24", "title": "A Microwave Microfluidic Sensor Based on a Dual-Mode Resonator for Dual-Sensing Applications", "description": "

In this paper, we propose a novel microwave microfluidic sensor with dual-sensing capability. The sensor is based on a dual-mode resonator that consists of a folded microstrip line loaded with interdigital lines and a stub at the plane of symmetry. Due to the specific configuration, the resonator exhibits two entirely independent resonant modes, which allows simultaneous sensing of two fluids using a resonance shift method. The sensor is designed in a multilayer configuration with the proposed resonator and two separated microfluidic channels\u2014one intertwined with the interdigital lines and the other positioned below the stub. The circuit has been fabricated using low-temperature co-fired ceramics technology and its performance was verified through the measurement of its responses for different fluids in the microfluidic channels. The results confirm the dual-sensing capability with zero mutual influence as well as good overall performance. Besides an excellent potential for dual-sensing applications, the proposed sensor is a good candidate for application in mixing fluids and cell counting.

", "keywords": ["dual-mode resonator", "Chemical technology", "microwave sensor", "microfluidics", "TP1-1185", "02 engineering and technology", "low-temperature co-fired ceramics", "7. Clean energy", "01 natural sciences", "Article", "0104 chemical sciences", "microwave sensor; dual-mode resonator; microstrip; microfluidics; low-temperature co-fired ceramics", "0202 electrical engineering", " electronic engineering", " information engineering", "microstrip"]}, "links": [{"href": "http://www.mdpi.com/1424-8220/17/12/2713/pdf"}, {"href": "https://www.mdpi.com/1424-8220/17/12/2713/pdf"}, {"href": "https://doi.org/PMC5750723"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/Sensors", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "PMC5750723", "name": "item", "description": "PMC5750723", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/PMC5750723"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2017-11-24T00:00:00Z"}}, {"id": "PMC6068504", "type": "Feature", "geometry": null, "properties": {"updated": "2026-07-27T16:30:26Z", "type": "Journal Article", "created": "2018-07-12", "title": "Biosensing System for Concentration Quantification of Magnetically Labeled E. coli in Water Samples", "description": "

Bacterial contamination of water sources (e.g., lakes, rivers and springs) from waterborne bacteria is a crucial water safety issue and its prevention is of the utmost significance since it threatens the health and well-being of wildlife, livestock, and human populations and can lead to serious illness and even death. Rapid and multiplexed measurement of such waterborne pathogens is vital and the challenge is to instantly detect in these liquid samples different types of pathogens with high sensitivity and specificity. In this work, we propose a biosensing system in which the bacteria are labelled with streptavidin coated magnetic markers (MPs\u2014magnetic particles) forming compounds (MLBs\u2014magnetically labelled bacteria). Video microscopy in combination with a particle tracking software are used for their detection and quantification. When the liquid containing the MLBs is introduced into the developed, microfluidic platform, the MLBs are accelerated towards the outlet by means of a magnetic field gradient generated by integrated microconductors, which are sequentially switched ON and OFF by a microcontroller. The velocities of the MLBs and that of reference MPs, suspended in the same liquid in a parallel reference microfluidic channel, are calculated and compared in real time by a digital camera mounted on a conventional optical microscope in combination with a particle trajectory tracking software. The MLBs will be slower than the reference MPs due to the enhanced Stokes\u2019 drag force exerted on them, resulting from their greater volume and altered hydrodynamic shape. The results of the investigation showed that the parameters obtained from this method emerged as reliable predictors for E. coli concentrations.

", "keywords": ["0301 basic medicine", "0303 health sciences", "magnetophoresis", "magnetic microparticles", "Chemical technology", "magnetic labeling", "Microfluidics", "TP1-1185", "Biosensing Techniques", "Article", "6. Clean water", "particle tracking", "Magnetics", "03 medical and health sciences", "bacteria quantification", "13. Climate action", "Escherichia coli", "biosensing", "Water Microbiology"]}, "links": [{"href": "http://www.mdpi.com/1424-8220/18/7/2250/pdf"}, {"href": "https://doi.org/PMC6068504"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/Sensors", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "PMC6068504", "name": "item", "description": "PMC6068504", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/PMC6068504"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2018-07-12T00:00:00Z"}}, {"id": "PMC9666553", "type": "Feature", "geometry": null, "properties": {"updated": "2026-07-27T16:30:33Z", "type": "Journal Article", "created": "2022-11-15", "title": "Microfluidic study in a meter-long reactive path reveals how the medium\u2019s structural heterogeneity shapes MICP-induced biocementation", "description": "Abstract

Microbially induced calcium carbonate (CaCO3) precipitation (MICP) is one of the major sustainable alternatives to the artificial cementation of granular media. MICP consists of injecting the soil with bacterial- and calcium-rich solutions sequentially to form calcite bonds among the soil particles that improve the strength and stiffness of soils. The performance of MICP is governed by the underlying microscale processes of bacterial growth, reactive transport of solutes, reaction rates, crystal nucleation and growth. However, the impact of pore-scale heterogeneity on these processes during MICP is not well understood. This paper sheds light on the effect of pore-scale heterogeneity on the spatiotemporal evolution of MICP, overall chemical reaction efficiency and permeability evolution by combining two meter-long microfluidic devices of identical dimensions and porosity with homogeneous and heterogeneous porous networks and real-time monitoring. The two chips received, in triplicate, MICP treatment with an imposed flow and the same initial conditions, while the inlet and outlet pressures were periodically monitored. This paper proposes a comprehensive workflow destined to detect bacteria and crystals from time-lapse microscopy data at multiple positions along a microfluidic replica of porous media treated with MICP. CaCO3 crystals were formed 1\uffc2\uffa0h after the introduction of the cementation solution (CS), and crystal growth was completed 12\uffc2\uffa0h later. The average crystal growth rate was overall higher in the heterogeneous porous medium, while it became slower after the first 3\uffc2\uffa0h of cementation injection. It was found that the average chemical reaction efficiency presented a peak of 34% at the middle of the chip and remained above 20% before the last 90\uffc2\uffa0mm of the reactive path for the heterogeneous porous network. The homogeneous porous medium presented an overall lower average reaction efficiency, which peaked at 27% 420\uffc2\uffa0mm downstream of the inlet and remained lower than 12% for the rest of the microfluidic channel. These different trends of chemical efficiency in the two networks are due to a higher number of crystals of higher average diameter in the heterogeneous medium than in the homogeneous porous medium. In the interval between 480 and 900\uffc2\uffa0mm, the number of crystals in the heterogeneous porous medium is more than double the number of crystals in the homogeneous porous medium. The average diameters of the crystals were 23\uffe2\uff80\uff9346\uffc2\uffa0\uffce\uffbcm in the heterogeneous porous medium, compared to 17\uffe2\uff80\uff9340\uffc2\uffa0\uffce\uffbcm in the homogeneous porous medium across the whole chip. The permeability of the heterogeneous porous medium was more affected than that of the homogeneous system, while the pressure sensors effectively captured a higher decrease in the permeability during the first two hours when crystals were formed and a less prominent decrease during the subsequent seeded growth of the existing crystals, as well as the nucleation and growth of new crystals.