{"type": "FeatureCollection", "features": [{"id": "10.1016/j.eja.2022.126569", "type": "Feature", "geometry": null, "properties": {"updated": "2026-09-21T16:15:33Z", "type": "Journal Article", "created": "2022-07-08", "title": "Mixing process-based and data-driven approaches in yield prediction", "description": "Yield prediction models can be divided between data-driven and process-based models (crop growth models). The first category contains many different types of models with parameters learned from the data themselves and where domain knowledge is only used to select the predictors and engineer features. In the second category, models are based upon biophysical principles, whose structure and parameters are derived primarily from domain knowledge. Here we investigate if the integration of the two approaches can be beneficial as it allows to overcome the limitations of the two approaches taken individually - lack of sufficiently large, reliable and orthogonal datasets for data-driven approaches and the need of many inputs for process-based models. The applications of the two categories of models have been reviewed, paying special attention to the cases where the two approaches have been mixed. By analysing the literature we identified three major cases of integration between the two approaches: (1) using crop growth models to engineer features and expand the predictors space, (2) use data-driven approaches to estimate missing inputs for process-based models (3) using data-driven approaches to produce meta-models to reduce computation burden. Finally we propose a methodology based on metamodels and transfer learning to integrate data-driven and process-based approaches.", "keywords": ["Process-based", "0106 biological sciences", "2. Zero hunger", "Artificial intelligence", "Crop growth models", "04 agricultural and veterinary sciences", "Data-driven", "01 natural sciences", "Yield prediction", "Dynamic crop growth models", "Surrogate models", "0401 agriculture", " forestry", " and fisheries", "Crop models", "Metamodels", "Neural networks"]}, "links": [{"href": "https://doi.org/10.1016/j.eja.2022.126569"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/European%20Journal%20of%20Agronomy", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "10.1016/j.eja.2022.126569", "name": "item", "description": "10.1016/j.eja.2022.126569", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/10.1016/j.eja.2022.126569"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2022-09-01T00:00:00Z"}}, {"id": "10.1021/acs.est.4c12247", "type": "Feature", "geometry": null, "properties": {"updated": "2026-09-21T16:16:32Z", "type": "Journal Article", "created": "2025-02-27", "title": "Predicting Toxicity toward Nitrifiers by Attention-Enhanced Graph Neural Networks and Transfer Learning from Baseline Toxicity", "description": "Assessing chemical environmental impacts is critical but challenging due to the time-consuming nature of experimental testing. Graph neural networks (GNNs) support superior prediction performance and mechanistic interpretation of (eco-)toxicity data, but face the risk of overfitting on the typically small experimental data sets. In contrast to purely data-driven approaches, we propose a mechanism-guided transfer learning strategy that is highly efficient and provides key insights into the underlying drivers of (eco-)toxicity. By leveraging the mechanistic link between baseline toxicity and toxicity toward nitrifiers, we pretrained a GNN on lipophilicity data (log P) and subsequently fine-tuned it on the limited data set of toxicity toward nitrifiers, achieving prediction performance comparable with pretraining on much larger but mechanistically less relevant data sets. Additionally, we enhanced GNN interpretability by adjusting multihead attentions after convolutional layers to identify key substructures, and quantified their contributions using a Shapley Value method adapted for graph-structured data with improved computational efficiency. The highlighted substructures aligned well with and effectively distinguished known structural alerts for baseline toxicity and specific modes of toxic action in nitrifiers. The proposed strategy will allow uncovering new structural alerts in other (eco)toxicity data, and thus foster new mechanistic insights to support chemical risk assessment and safe-by-design principles.", "keywords": ["Neural Networks", " Computer", "Nitrification"]}, "links": [{"href": "https://doi.org/10.1021/acs.est.4c12247"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/Environmental%20Science%20%26amp%3B%20Technology", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "10.1021/acs.est.4c12247", "name": "item", "description": "10.1021/acs.est.4c12247", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/10.1021/acs.est.4c12247"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2025-02-27T00:00:00Z"}}, {"id": "10.1093/jxb/erab174", "type": "Feature", "geometry": null, "properties": {"updated": "2026-09-21T16:17:16Z", "type": "Journal Article", "created": "2020-12-03", "title": "Digging roots is easier with AI", "description": "Abstract<p>The scale of root quantification in research is often limited by the time required for sampling, measurement and processing samples. Recent developments in Convolutional Neural Networks (CNN) have made faster and more accurate plant image analysis possible which may significantly reduce the time required for root measurement, but challenges remain in making these methods accessible to researchers without an in-depth knowledge of Machine Learning. We analyzed root images acquired from three destructive root samplings using the RootPainter CNN-software that features an interface for corrective annotation for easier use. Root scans with and without non-root debris were used to test if training a model, i.e., learning from labeled examples, can effectively exclude the debris by comparing the end-results with measurements from clean images. Root images acquired from soil profile walls and the cross-section of soil cores were also used for training and the derived measurements were compared with manual measurements. After 200 minutes of training on each dataset, significant relationships between manual measurements and RootPainter-derived data were noted for monolith (R2=0.99), profile wall (R2=0.76) and core-break (R2=0.57). The rooting density derived from images with debris was not significantly different from that derived from clean images after processing with RootPainter. Rooting density was also successfully calculated from both profile wall and soil core images, and in each case the gradient of root density with depth was not significantly different from manual counts. Our results demonstrate that the proposed approach using CNN can lead to substantial reductions in root sample processing workloads, increasing the potential scale of future root investigations.</p>", "keywords": ["0301 basic medicine", "root phenotyping", "profile wall", "root washing", "segmentation", "deep learning", "Convolutional neural network", "04 agricultural and veterinary sciences", "15. Life on land", "Soil", "03 medical and health sciences", "core-break", "monolith", "soil coring", "Image Processing", " Computer-Assisted", "0401 agriculture", " forestry", " and fisheries", "Neural Networks", " Computer", "Software"]}, "links": [{"href": "http://academic.oup.com/jxb/article-pdf/72/13/4680/38807872/erab174.pdf"}, {"href": "https://doi.org/10.1093/jxb/erab174"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/Journal%20of%20Experimental%20Botany", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "10.1093/jxb/erab174", "name": "item", "description": "10.1093/jxb/erab174", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/10.1093/jxb/erab174"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2020-12-02T00:00:00Z"}}, {"id": "10.1093/mnras/staa3201", "type": "Feature", "geometry": null, "properties": {"updated": "2026-09-21T16:17:17Z", "type": "Journal Article", "created": "2020-10-16", "title": "Quantifying the structure of strong gravitational lens potentials with uncertainty-aware deep neural networks", "description": "ABSTRACT<p>Gravitational lensing is a powerful tool for constraining substructure in the mass distribution of galaxies, be it from the presence of dark matter sub-haloes or due to physical mechanisms affecting the baryons throughout galaxy evolution. Such substructure is hard to model and is either ignored by traditional, smooth modelling, approaches, or treated as well-localized massive perturbers. In this work, we propose a deep learning approach to quantify the statistical properties of such perturbations directly from images, where only the extended lensed source features within a mask are considered, without the need of any lens modelling. Our training data consist of mock lensed images assuming perturbing Gaussian Random Fields permeating the smooth overall lens potential, and, for the first time, using images of real galaxies as the lensed source. We employ a novel deep neural network that can handle arbitrary uncertainty intervals associated with the training data set labels as input, provides probability distributions as output, and adopts a composite loss function. The method succeeds not only in accurately estimating the actual parameter values, but also reduces the predicted confidence intervals by 10\uffc2\uffa0per\uffe2\uff80\uff89cent in an unsupervised manner, i.e. without having access to the actual ground truth values. Our results are invariant to the inherent degeneracy between mass perturbations in the lens and complex brightness profiles for the source. Hence, we can quantitatively and robustly quantify the smoothness of the mass density of thousands of lenses, including confidence intervals, and provide a consistent ranking for follow-up science.</p>", "keywords": ["Physics", "Gravitational lens", "Space and Planetary Science", "Astrophysics of Galaxies (astro-ph.GA)", "0103 physical sciences", "Deep neural networks", "FOS: Physical sciences", "Astronomy and Astrophysics", "Statistical physics", "Astrophysics - Astrophysics of Galaxies", "01 natural sciences"]}, "links": [{"href": "http://academic.oup.com/mnras/article-pdf/499/4/5641/34141333/staa3201.pdf"}, {"href": "https://doi.org/10.1093/mnras/staa3201"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/Monthly%20Notices%20of%20the%20Royal%20Astronomical%20Society", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "10.1093/mnras/staa3201", "name": "item", "description": "10.1093/mnras/staa3201", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/10.1093/mnras/staa3201"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2020-10-17T00:00:00Z"}}, {"id": "10.1111/nph.15123", "type": "Feature", "geometry": null, "properties": {"updated": "2026-09-21T16:17:53Z", "type": "Journal Article", "created": "2018-03-31", "title": "Quantifying soil moisture impacts on light use efficiency across biomes", "description": "Summary<p>   <p>Terrestrial primary productivity and carbon cycle impacts of droughts are commonly quantified using vapour pressure deficit (VPD) data and remotely sensed greenness, without accounting for soil moisture. However, soil moisture limitation is known to strongly affect plant physiology.</p>  <p>Here, we investigate light use efficiency, the ratio of gross primary productivity (GPP) to absorbed light. We derive its fractional reduction due to soil moisture (fLUE), separated from VPD and greenness changes, using artificial neural networks trained on eddy covariance data, multiple soil moisture datasets and remotely sensed greenness.</p>  <p>This reveals substantial impacts of soil moisture alone that reduce GPP by up to 40% at sites located in sub\uffe2\uff80\uff90humid, semi\uffe2\uff80\uff90arid or arid regions. For sites in relatively moist climates, we find, paradoxically, a muted fLUE response to drying soil, but reduced fLUE under wet conditions.</p>  <p>fLUE identifies substantial drought impacts that are not captured when relying solely on VPD and greenness changes and, when seasonally recurring, are missed by traditional, anomaly\uffe2\uff80\uff90based drought indices. Counter to common assumptions, fLUE reductions are largest in drought\uffe2\uff80\uff90deciduous vegetation, including grasslands. Our results highlight the necessity to account for soil moisture limitation in terrestrial primary productivity data products, especially for drought\uffe2\uff80\uff90related assessments.</p>  </p>", "keywords": ["Time Factors", "550", "vapour pressure deficit", "Light", "Vapor Pressure", "Rain", "Eddy covariance", "02 engineering and technology", "01 natural sciences", "630", "Ecological applications", "Soil", "drought impacts", "Vapour pressure deficit", "Photosynthesis", "drought impacts; eddy covariance; gross primary productivity (GPP); light use efficiency; photosynthesis; soil moisture; standardized precipitation index; vapour pressure deficit (VPD)", "Plant biology", "2. Zero hunger", "Light use efficiency", "Ecology", "gross primary productivity (GPP)", "Biological Sciences", "6. Clean water", "Droughts", "Climate change impacts and adaptation", "gross primary productivity", "Neural Networks", "Plant Biology & Botany", "Drought impacts", "vapour pressure deficit (VPD)", "0207 environmental engineering", "Computer", "eddy covariance", "light use efficiency", "Ecosystem", "0105 earth and related environmental sciences", "photosynthesis", "Agricultural and Veterinary Sciences", "Research", "Gross primary productivity ()", "Water", "Humidity", "Plant Transpiration", "06 Biological Sciences", "15. Life on land", "standardized precipitation index", "13. Climate action", "vapour pressure deficit (VPD", "Standardized precipitation index", "07 Agricultural And Veterinary Sciences", "Soil moisture", "Neural Networks", " Computer", "soil moisture", "Climate Change Impacts and Adaptation", "Environmental Sciences"]}, "links": [{"href": "https://nph.onlinelibrary.wiley.com/doi/pdf/10.1111/nph.15123"}, {"href": "https://escholarship.org/content/qt3sb2745c/qt3sb2745c.pdf"}, {"href": "https://doi.org/10.1111/nph.15123"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/New%20Phytologist", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "10.1111/nph.15123", "name": "item", "description": "10.1111/nph.15123", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/10.1111/nph.15123"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2018-03-31T00:00:00Z"}}, {"id": "10.1111/nph.18387", "type": "Feature", "geometry": null, "properties": {"updated": "2026-09-21T16:17:54Z", "type": "Journal Article", "created": "2020-04-18", "title": "RootPainter: deep learning segmentation of biological images with corrective annotation", "description": "<p>We present RootPainter, a GUI-based software tool for the rapid training of deep neural networks for use in biological image analysis. RootPainter facilitates both fully-automatic and semi-automatic image segmentation. We investigate the effectiveness of RootPainter using three plant image datasets, evaluating its potential for root length extraction from chicory roots in soil, biopore counting and root nodule counting from scanned roots. We also use RootPainter to compare dense annotations to corrective ones which are added during the training based on the weaknesses of the current model.</p>", "keywords": ["Buildings and machinery", "0301 basic medicine", "phenotyping", "root nodule", "biopore", "interactive machine learning", "Research", "segmentation", "deep learning", "rhizotron", "Breeding and genetics", "Machine Learning", "Soil", "03 medical and health sciences", "Deep Learning", "GUI", "Farm nutrient management", "Image Processing", " Computer-Assisted", "Neural Networks", " Computer"]}, "links": [{"href": "https://www.biorxiv.org/content/10.1101/2020.04.16.044461v1.full.pdf"}, {"href": "https://nph.onlinelibrary.wiley.com/doi/pdf/10.1111/nph.18387"}, {"href": "https://doi.org/10.1111/nph.18387"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/New%20Phytologist", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "10.1111/nph.18387", "name": "item", "description": "10.1111/nph.18387", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/10.1111/nph.18387"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2020-04-18T00:00:00Z"}}, {"id": "10.1364/cleo_qels.2019.ff3b.6", "type": "Feature", "geometry": null, "properties": {"updated": "2026-09-21T16:18:14Z", "type": "Journal Article", "created": "2019-05-07", "title": "Disorder-Immune Photonics Based on Mie-Resonant Dielectric Metamaterials", "description": "Open Access6 pages, 5 figures", "keywords": ["Optics and Photonics", "Photons", "F300", "H600", "FOS: Physical sciences", "535", "Physics - Applied Physics", "Applied Physics (physics.app-ph)", "Disordered Systems and Neural Networks (cond-mat.dis-nn)", "02 engineering and technology", "Condensed Matter - Disordered Systems and Neural Networks", "Models", " Theoretical", "0210 nano-technology", "Physics - Optics", "Optics (physics.optics)"]}, "links": [{"href": "https://nrl.northumbria.ac.uk/id/eprint/47159/1/LE17739_2_.pdf"}, {"href": "https://openresearch-repository.anu.edu.au/bitstream/1885/214130/3/01_Liu_Disorder-Immune_Photonics_2019.pdf.jpg"}, {"href": "https://doi.org/10.1364/cleo_qels.2019.ff3b.6"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/Conference%20on%20Lasers%20and%20Electro-Optics", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "10.1364/cleo_qels.2019.ff3b.6", "name": "item", "description": "10.1364/cleo_qels.2019.ff3b.6", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/10.1364/cleo_qels.2019.ff3b.6"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2019-01-01T00:00:00Z"}}, {"id": "10.1371/journal.pone.0125404", "type": "Feature", "geometry": null, "properties": {"updated": "2026-09-21T16:18:17Z", "type": "Journal Article", "created": "2015-05-06", "title": "The Contribution Of Mangrove Expansion To Salt Marsh Loss On The Texas Gulf Coast", "description": "Landscape-level shifts in plant species distribution and abundance can fundamentally change the ecology of an ecosystem. Such shifts are occurring within mangrove-marsh ecotones, where over the last few decades, relatively mild winters have led to mangrove expansion into areas previously occupied by salt marsh plants. On the Texas (USA) coast of the western Gulf of Mexico, most cases of mangrove expansion have been documented within specific bays or watersheds. Based on this body of relatively small-scale work and broader global patterns of mangrove expansion, we hypothesized that there has been a recent regional-level displacement of salt marshes by mangroves. We classified Landsat-5 Thematic Mapper images using artificial neural networks to quantify black mangrove (Avicennia germinans) expansion and salt marsh (Spartina alterniflora and other grass and forb species) loss over 20 years across the entire Texas coast. Between 1990 and 2010, mangrove area grew by 16.1 km(2), a 74% increase. Concurrently, salt marsh area decreased by 77.8 km(2), a 24% net loss. Only 6% of that loss was attributable to mangrove expansion; most salt marsh was lost due to conversion to tidal flats or water, likely a result of relative sea level rise. Our research confirmed that mangroves are expanding and, in some instances, displacing salt marshes at certain locations. However, this shift is not widespread when analyzed at a larger, regional level. Rather, local, relative sea level rise was indirectly implicated as another important driver causing regional-level salt marsh loss. Climate change is expected to accelerate both sea level rise and mangrove expansion; these mechanisms are likely to interact synergistically and contribute to salt marsh loss.", "keywords": ["Satellite Imagery", "0106 biological sciences", "Science", "Climate Change", "Marshes", "Poaceae", "01 natural sciences", "333", "Image Interpretation", " Computer-Assisted", "11. Sustainability", "14. Life underwater", "Mangrove swamps", "Ecosystem", "0105 earth and related environmental sciences", "Gulf of Mexico", "Artificial neural networks", "Winter", "Q", "R", "15. Life on land", "Texas", "Habitats", "13. Climate action", "Wetlands", "Medicine", "Avicennia", "Seasons", "Research Article"], "contacts": [{"organization": "Armitage, Anna R., Highfield, Wesley E., Brody, Samuel D., Louchouarn, Patrick,", "roles": ["creator"]}]}, "links": [{"href": "https://doi.org/10.1371/journal.pone.0125404"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/PLOS%20ONE", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "10.1371/journal.pone.0125404", "name": "item", "description": "10.1371/journal.pone.0125404", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/10.1371/journal.pone.0125404"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2015-05-06T00:00:00Z"}}, {"id": "10.3390/drones7030179", "type": "Feature", "geometry": null, "properties": {"updated": "2026-09-21T16:19:22Z", "type": "Journal Article", "created": "2023-03-07", "title": "Animal Detection and Counting from UAV Images Using Convolutional Neural Networks", "description": "<?xml version='1.0' encoding='UTF-8'?><article><p>In the last decade, small unmanned aerial vehicles (UAVs/drones) have become increasingly popular in the airborne observation of large areas for many purposes, such as the monitoring of agricultural areas, the tracking of wild animals in their natural habitats, and the counting of livestock. Coupled with deep learning, they allow for automatic image processing and recognition. The aim of this work was to detect and count the deer population in northwestern Serbia from such images using deep neural networks, a tedious process that otherwise requires a lot of time and effort. In this paper, we present and compare the performance of several state-of-the-art network architectures, trained on a manually annotated set of images, and use it to predict the presence of objects in the rest of the dataset. We implemented three versions of the You Only Look Once (YOLO) architecture and a Single Shot Multibox Detector (SSD) to detect deer in a dense forest environment and measured their performance based on mean average precision (mAP), precision, recall, and F1 score. Moreover, we also evaluated the models based on their real-time performance. The results showed that the selected models were able to detect deer with a mean average precision of up to 70.45% and a confidence score of up to a 99%. The highest precision was achieved by the fourth version of YOLO with 86%, as well as the highest recall value of 75%. Its compressed version achieved slightly lower results, with 83% mAP in its best case, but it demonstrated four times better real-time performance. The counting function was applied on the best-performing models, providing us with the exact distribution of deer over all images. Yolov4 obtained an error of 8.3% in counting, while Yolov4-tiny mistook 12 deer, which accounted for an error of 7.1%.</p></article>", "keywords": ["convolutional neural networks; deer; animal counting; deep learning; YOLO; SSD", "convolutional neural networks", "deer", "deep learning", "YOLO", "TL1-4050", "animal counting", "SSD", "Motor vehicles. Aeronautics. Astronautics"]}, "links": [{"href": "http://www.mdpi.com/2504-446X/7/3/179/pdf"}, {"href": "https://www.mdpi.com/2504-446X/7/3/179/pdf"}, {"href": "https://doi.org/10.3390/drones7030179"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/Drones", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "10.3390/drones7030179", "name": "item", "description": "10.3390/drones7030179", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/10.3390/drones7030179"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2023-03-06T00:00:00Z"}}, {"id": "10.3390/ijms24076573", "type": "Feature", "geometry": null, "properties": {"updated": "2026-09-21T16:19:24Z", "type": "Journal Article", "created": "2023-04-03", "title": "A Systematic Review of Deep Learning Methodologies Used in the Drug Discovery Process with Emphasis on In Vivo Validation", "description": "<?xml version='1.0' encoding='UTF-8'?><article><p>The discovery and development of new drugs are extremely long and costly processes. Recent progress in artificial intelligence has made a positive impact on the drug development pipeline. Numerous challenges have been addressed with the growing exploitation of drug-related data and the advancement of deep learning technology. Several model frameworks have been proposed to enhance the performance of deep learning algorithms in molecular design. However, only a few have had an immediate impact on drug development since computational results may not be confirmed experimentally. This systematic review aims to summarize the different deep learning architectures used in the drug discovery process and are validated with further in vivo experiments. For each presented study, the proposed molecule or peptide that has been generated or identified by the deep learning model has been biologically evaluated in animal models. These state-of-the-art studies highlight that even if artificial intelligence in drug discovery is still in its infancy, it has great potential to accelerate the drug discovery cycle, reduce the required costs, and contribute to the integration of the 3R (Replacement, Reduction, Refinement) principles. Out of all the reviewed scientific articles, seven algorithms were identified: recurrent neural networks, specifically, long short-term memory (LSTM-RNNs), Autoencoders (AEs) and their Wasserstein Autoencoders (WAEs) and Variational Autoencoders (VAEs) variants; Convolutional Neural Networks (CNNs); Direct Message Passing Neural Networks (D-MPNNs); and Multitask Deep Neural Networks (MTDNNs). LSTM-RNNs were the most used architectures with molecules or peptide sequences as inputs.</p></article>", "keywords": ["Deep Learning", "Artificial Intelligence", "Drug Discovery", "Review", "Neural Networks", " Computer", "drug discovery; drug design; artificial intelligence; machine learning; deep learning; biological evaluation; animal model; in vivo", "Algorithms", "3. Good health"]}, "links": [{"href": "https://www.mdpi.com/1422-0067/24/7/6573/pdf"}, {"href": "https://doi.org/10.3390/ijms24076573"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/International%20Journal%20of%20Molecular%20Sciences", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "10.3390/ijms24076573", "name": "item", "description": "10.3390/ijms24076573", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/10.3390/ijms24076573"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2023-03-31T00:00:00Z"}}, {"id": "10.3390/rs14030634", "type": "Feature", "geometry": null, "properties": {"updated": "2026-09-21T16:19:30Z", "type": "Journal Article", "created": "2022-01-29", "title": "4D U-Nets for Multi-Temporal Remote Sensing Data Classification", "description": "<p>Multispectral sensors constitute a core earth observation imaging technology generating massive high-dimensional observations acquired across multiple time instances. The collected multi-temporal remote sensed data contain rich information for Earth monitoring applications, from flood detection to crop classification. To easily classify such naturally multidimensional data, conventional low-order deep learning models unavoidably toss away valuable information residing across the available dimensions. In this work, we extend state-of-the-art convolutional network models based on the U-Net architecture to their high-dimensional analogs, which can naturally capture multi-dimensional dependencies and correlations. We introduce several model architectures, both of low as well as of high order, and we quantify the achieved classification performance vis-\uffc3\uffa0-vis the latest state-of-the-art methods. The experimental analysis on observations from Landsat-8 reveals that approaches based on low-order U-Net models exhibit poor classification performance and are outperformed by our proposed high-dimensional U-Net scheme.</p>", "keywords": ["remote sensing", "multi-temporal data classification", "Science", "Q", "0211 other engineering and technologies", "0401 agriculture", " forestry", " and fisheries", "04 agricultural and veterinary sciences", "02 engineering and technology", "u-nets", "higher-order convolutional neural networks"]}, "links": [{"href": "http://www.mdpi.com/2072-4292/14/3/634/pdf"}, {"href": "https://www.mdpi.com/2072-4292/14/3/634/pdf"}, {"href": "https://doi.org/10.3390/rs14030634"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/Remote%20Sensing", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "10.3390/rs14030634", "name": "item", "description": "10.3390/rs14030634", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/10.3390/rs14030634"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2022-01-28T00:00:00Z"}}, {"id": "10.3390/soilsystems9010010", "type": "Feature", "geometry": null, "properties": {"license": "Open Access", "updated": "2026-09-21T16:19:32Z", "type": "Journal Article", "created": "2025-01-27", "title": "Application of Self-Organizing Maps to Explore the Interactions of Microorganisms with Soil Properties in Fruit Crops Under Different Management and Pedo-Climatic Conditions", "description": "<?xml version='1.0' encoding='UTF-8'?><article><p>Background: Self-organizing maps (SOMs) are a class of neural network algorithms able to visually describe a high-dimensional dataset onto a two-dimensional grid. SOMs were explored to classify soils based on an array of physical, chemical, and biological parameters. Methods: The SOM analysis was performed considering soil physical, chemical, and microbial data gathered from an array of apple orchards and strawberry plantations managed by organic or conventional methods and located in different European climatic zones. Results: The SOM analysis considering the \u201cclimatic zone\u201d categorical variables was able to discriminate the samples from the three zones for both crops. The zones were associated with different soil textures and chemical characteristics, and for both crops, the Continental zone was associated with microbial parameters\u2014including biodiversity indices derived from the NGS data analysis. However, the SOM analysis based on the \u201cmanagement method\u201d categorical variables was not able to discriminate the soils between organic and integrated management. Conclusions: This study allowed for the discrimination of soils of medium- and long-term fruit crops based on their pedo-climatic characteristics and associating these characteristics to some indicators of the soil biome, pointing to the possibility of better understanding the interactions among diverse variables, which could support unraveling the intricate web of relationships that define soil quality.</p></article>", "keywords": ["Physical geography", "Chemistry", "soil microbiome diversity", "apple", "strawberry", "neural networks", "QD1-999", "GB3-5030"]}, "links": [{"href": "https://www.mdpi.com/2571-8789/9/1/10/pdf"}, {"href": "https://doi.org/10.3390/soilsystems9010010"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/Soil%20Systems", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "10.3390/soilsystems9010010", "name": "item", "description": "10.3390/soilsystems9010010", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/10.3390/soilsystems9010010"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2025-01-26T00:00:00Z"}}, {"id": "10.5281/zenodo.3463412", "type": "Feature", "geometry": null, "properties": {"updated": "2026-09-21T16:21:05Z", "type": "Journal Article", "title": "Prediction of liquefaction damage with artificial neural networks", "description": "The survey of the damage occurred on land, buildings and infrastructures<br> extensively affected by liquefaction, coupled with a comprehensive investigation of the subsoil<br> properties enables to identify the factors that determine the spatial distribution of the phenomenon.<br> With this goal, a database was created in a Geographic Information platform merging<br> records of local seismicity, subsoil layering evaluated by cone penetration tests and<br> groundwater level distribution for the relevant case study of San Carlo (Emilia Romagna-<br> Italy) struck by a severe earthquake in 2012. Here liquefaction phenomena were observed on a<br> portion of the village in the form of sand ejecta, lateral spreading and various damages on<br> buildings and infrastructures. The location of damage allows to test possible relations with the<br> factors characterizing susceptibility, triggering and severity of liquefaction. The relation<br> among the different variables has been herein sought by training a specifically implemented<br> Artificial Neural Network. A relation has thus been inferred between damage and thickness of<br> the liquefiable layer and of the upper crust, seismic input and soil characteristics.", "keywords": ["Liquefaction", "Liquefaction", " Artificial Neural Networks", "0211 other engineering and technologies", "02 engineering and technology", "Artificial Neural Networks"], "contacts": [{"organization": "Paolella Luca, Erminio, Salvatore, Spacagna Rose Line, Modoni Giuseppe, Ochmanski Maciej,", "roles": ["creator"]}]}, "links": [{"href": "https://doi.org/10.5281/zenodo.3463412"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/Earthquake%20Geotechnical%20Engineering%20for%20Protection%20an%20Development%20of%20Environment", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "10.5281/zenodo.3463412", "name": "item", "description": "10.5281/zenodo.3463412", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/10.5281/zenodo.3463412"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2019-01-01T00:00:00Z"}}, {"id": "10044/1/59029", "type": "Feature", "geometry": null, "properties": {"updated": "2026-09-21T16:21:59Z", "type": "Journal Article", "created": "2018-03-31", "title": "Quantifying soil moisture impacts on light use efficiency across biomes", "description": "Summary<p>   <p>Terrestrial primary productivity and carbon cycle impacts of droughts are commonly quantified using vapour pressure deficit (VPD) data and remotely sensed greenness, without accounting for soil moisture. However, soil moisture limitation is known to strongly affect plant physiology.</p>  <p>Here, we investigate light use efficiency, the ratio of gross primary productivity (GPP) to absorbed light. We derive its fractional reduction due to soil moisture (fLUE), separated from VPD and greenness changes, using artificial neural networks trained on eddy covariance data, multiple soil moisture datasets and remotely sensed greenness.</p>  <p>This reveals substantial impacts of soil moisture alone that reduce GPP by up to 40% at sites located in sub\uffe2\uff80\uff90humid, semi\uffe2\uff80\uff90arid or arid regions. For sites in relatively moist climates, we find, paradoxically, a muted fLUE response to drying soil, but reduced fLUE under wet conditions.</p>  <p>fLUE identifies substantial drought impacts that are not captured when relying solely on VPD and greenness changes and, when seasonally recurring, are missed by traditional, anomaly\uffe2\uff80\uff90based drought indices. Counter to common assumptions, fLUE reductions are largest in drought\uffe2\uff80\uff90deciduous vegetation, including grasslands. Our results highlight the necessity to account for soil moisture limitation in terrestrial primary productivity data products, especially for drought\uffe2\uff80\uff90related assessments.</p>  </p", "keywords": ["Time Factors", "550", "vapour pressure deficit", "Light", "Vapor Pressure", "Rain", "Eddy covariance", "02 engineering and technology", "01 natural sciences", "630", "Ecological applications", "Soil", "drought impacts", "Vapour pressure deficit", "Photosynthesis", "drought impacts; eddy covariance; gross primary productivity (GPP); light use efficiency; photosynthesis; soil moisture; standardized precipitation index; vapour pressure deficit (VPD)", "Plant biology", "2. Zero hunger", "Light use efficiency", "Ecology", "gross primary productivity (GPP)", "Biological Sciences", "6. Clean water", "Droughts", "Climate change impacts and adaptation", "gross primary productivity", "Neural Networks", "Plant Biology & Botany", "Drought impacts", "vapour pressure deficit (VPD)", "0207 environmental engineering", "Computer", "eddy covariance", "light use efficiency", "Ecosystem", "0105 earth and related environmental sciences", "photosynthesis", "Agricultural and Veterinary Sciences", "Research", "Gross primary productivity ()", "Water", "Humidity", "Plant Transpiration", "06 Biological Sciences", "15. Life on land", "standardized precipitation index", "13. Climate action", "vapour pressure deficit (VPD", "Standardized precipitation index", "07 Agricultural And Veterinary Sciences", "Soil moisture", "Neural Networks", " Computer", "soil moisture", "Climate Change Impacts and Adaptation", "Environmental Sciences"]}, "links": [{"href": "https://nph.onlinelibrary.wiley.com/doi/pdf/10.1111/nph.15123"}, {"href": "https://escholarship.org/content/qt3sb2745c/qt3sb2745c.pdf"}, {"href": "https://doi.org/10044/1/59029"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/New%20Phytologist", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "10044/1/59029", "name": "item", "description": "10044/1/59029", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/10044/1/59029"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2018-03-31T00:00:00Z"}}, {"id": "1885/214130", "type": "Feature", "geometry": null, "properties": {"updated": "2026-09-21T16:22:28Z", "type": "Journal Article", "created": "2019-05-07", "title": "Disorder-Immune Photonics Based on Mie-Resonant Dielectric Metamaterials", "description": "Open Access6 pages, 5 figures", "keywords": ["Optics and Photonics", "Photons", "F300", "H600", "FOS: Physical sciences", "535", "Physics - Applied Physics", "Applied Physics (physics.app-ph)", "Disordered Systems and Neural Networks (cond-mat.dis-nn)", "02 engineering and technology", "Condensed Matter - Disordered Systems and Neural Networks", "Models", " Theoretical", "0210 nano-technology", "Physics - Optics", "Optics (physics.optics)"]}, "links": [{"href": "https://nrl.northumbria.ac.uk/id/eprint/47159/1/LE17739_2_.pdf"}, {"href": "https://openresearch-repository.anu.edu.au/bitstream/1885/214130/3/01_Liu_Disorder-Immune_Photonics_2019.pdf.jpg"}, {"href": "https://doi.org/1885/214130"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/Conference%20on%20Lasers%20and%20Electro-Optics", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "1885/214130", "name": "item", "description": "1885/214130", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/1885/214130"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2019-01-01T00:00:00Z"}}, {"id": "PMC10095548", "type": "Feature", "geometry": null, "properties": {"updated": "2026-09-21T16:24:37Z", "type": "Journal Article", "created": "2023-04-03", "title": "A Systematic Review of Deep Learning Methodologies Used in the Drug Discovery Process with Emphasis on In Vivo Validation", "description": "<?xml version='1.0' encoding='UTF-8'?><article><p>The discovery and development of new drugs are extremely long and costly processes. Recent progress in artificial intelligence has made a positive impact on the drug development pipeline. Numerous challenges have been addressed with the growing exploitation of drug-related data and the advancement of deep learning technology. Several model frameworks have been proposed to enhance the performance of deep learning algorithms in molecular design. However, only a few have had an immediate impact on drug development since computational results may not be confirmed experimentally. This systematic review aims to summarize the different deep learning architectures used in the drug discovery process and are validated with further in vivo experiments. For each presented study, the proposed molecule or peptide that has been generated or identified by the deep learning model has been biologically evaluated in animal models. These state-of-the-art studies highlight that even if artificial intelligence in drug discovery is still in its infancy, it has great potential to accelerate the drug discovery cycle, reduce the required costs, and contribute to the integration of the 3R (Replacement, Reduction, Refinement) principles. Out of all the reviewed scientific articles, seven algorithms were identified: recurrent neural networks, specifically, long short-term memory (LSTM-RNNs), Autoencoders (AEs) and their Wasserstein Autoencoders (WAEs) and Variational Autoencoders (VAEs) variants; Convolutional Neural Networks (CNNs); Direct Message Passing Neural Networks (D-MPNNs); and Multitask Deep Neural Networks (MTDNNs). LSTM-RNNs were the most used architectures with molecules or peptide sequences as inputs.</p></article>", "keywords": ["Deep Learning", "Artificial Intelligence", "Drug Discovery", "Review", "Neural Networks", " Computer", "Algorithms", "3. Good health"]}, "links": [{"href": "https://www.mdpi.com/1422-0067/24/7/6573/pdf"}, {"href": "https://doi.org/PMC10095548"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/International%20Journal%20of%20Molecular%20Sciences", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "PMC10095548", "name": "item", "description": "PMC10095548", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/PMC10095548"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2023-03-31T00:00:00Z"}}, {"id": "f57c2c7f-f2fc-454d-a1d8-3f9dfe79e6ef", "type": "Feature", "geometry": {"type": "Polygon", "coordinates": [[[5.81, 47.26], [5.81, 54.76], [15.77, 54.76], [15.77, 47.26], [5.81, 47.26]]]}, "properties": {"themes": [{"concepts": [{"id": "farming"}], "scheme": "https://standards.iso.org/iso/19139/resources/gmxCodelists.xml#MD_TopicCategoryCode"}, {"concepts": [{"id": "neural networks"}, {"id": "magnetic resonance imaging"}, {"id": "root architecture"}, {"id": "environmental modelling"}, {"id": "agriculture"}, {"id": "plant water relations"}, {"id": "hydraulic conductivity"}], "scheme": "AGROVOC Multilingual agricultural thesaurus"}, {"concepts": [{"id": "opendata"}], "scheme": "Individual"}, {"concepts": [{"id": "Boden"}], "scheme": "GEMET - INSPIRE themes, version 1.0"}, {"concepts": [{"id": "non-geographic"}], "scheme": "individual"}], "rights": "Restrictions applied to assure the protection of privacy or intellectual property, and any special restrictions or limitations or warnings on using the resource or metadata. Reports, articles, papers, scientific and non - scientific works of any form, including tables, maps, or any other kind of output, in printed or electronic form, based in whole or in part on the data supplied, must contain an acknowledgement of the form: \"Data reused from the BonaRes Data Centre www.bonares.de. This data were created as part of the BonaRes Module A-Project - BonaRes - Soil3's research activities.\" Although every care has been taken in preparing and testing the data, the BonaRes Module A-Project - BonaRes - Soil3 and the BonaRes Data Centre cannot guarantee that the data are correct; neither does the BonaRes Module A-Project - BonaRes - Soil3 and the BonaRes Data Centre accept any liability whatsoever for any error, missing data or omission in the data, or for any loss or damage arising from its use. The BonaRes Module A-Project - BonaRes - Soil3 and BonaRes Data Centre will not be responsible for any direct or indirect use which might be made of the data.", "updated": "2025-11-03", "type": "Dataset", "created": "2025-10-13", "language": "eng", "title": "Code and simulation results of the paper: \u201c3D U-Net Segmentation Improves Root System Reconstruction from 3D MRI Images in Automated and Manual Virtual Reality Work Flows\u201d", "description": "This file contains the code and simulation results supporting the paper: \u201c3D U-Net Segmentation Improves Root System Reconstruction from 3D MRI Images in Automated and Manual Virtual Reality Work Flows\u201d\n\nDOI: https://doi.org/10.34133/plantphenomics.0076", "formats": [{"name": "CSV"}], "keywords": ["neural networks", "magnetic resonance imaging", "root architecture", "environmental modelling", "agriculture", "plant water relations", "hydraulic conductivity", "opendata", "Boden", "non-geographic"], "contacts": [{"name": "Leibniz Centre for Agricultural Landscape Research", "organization": "ZALF", "position": "Research Platform 'Data Analysis & Simulation' - Workgroup Research Data Management", "roles": ["publisher"], "phones": [{"value": "+49 33432 82 300"}], "emails": [{"value": "dataservice@zalf.de"}], "addresses": [{"deliveryPoint": ["Eberswalder Strasse 84"], "city": "M\u00fcncheberg", "administrativeArea": "Brandenburg", "postalCode": "15374", "country": "Germany"}], "links": [{"href": null}]}, {"name": "Tobias Selzner", "organization": "Forschungszentrum J\u00fclich", "position": null, "roles": ["author"], "phones": [{"value": null}], "emails": [{"value": "t.selzner@fz-juelich.de"}], "addresses": [{"deliveryPoint": [null], "city": null, "administrativeArea": null, "postalCode": null, "country": null}], "links": [{"href": {"url": null, "protocol": null, "protocol_url": "", "name": "0000-0003-1454-5450", "name_url": "", "description": "ORCID", "description_url": "", "applicationprofile": null, "applicationprofile_url": "", "function": null}}]}, {"name": "Anne E. 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