Extensive application of clustering and classification algorithms shows the potential of a CNT-based sensor array in breathomics.
Integrating photoactive proteins with synthetic nanomaterials holds great promise in developing optoelectronic devices whereby light, captured by a antenna protein, is converted to a modulated electrical response. The protein\uffe2\uff80\uff93nanomaterial interface is critical to defining optoelectronic properties; successful integration of bionanohybrids requires control over protein attachment site and a detailed understanding of its impact on device performance. Here, the first single\uffe2\uff80\uff90walled carbon nanotube (SWCNT) bio\uffe2\uff80\uff90optoelectronic transistor enabled by the site\uffe2\uff80\uff90specific direct interfacing with a green fluorescent protein (GFP) via genetically encoded phenyl azide photochemistry is reported. The electrical behavior of individual semiconducting SWCNTs depends on the protein residue coupling site and provides the basis to design eco\uffe2\uff80\uff90friendly phototransistors and optoelectronic memory. Attachment at one GFP residue proximal to the chromophore produces a wavelength\uffe2\uff80\uff90specific phototransistor. The bio\uffe2\uff80\uff90transistor can be switched off in less than 38 s with responsivity up to 7 \uffc3\uff97 103 A W\uffe2\uff88\uff921 at 470\uffc2\uffa0nm. Attachment via a second residue distal to the chromophore generates optoelectronic memory that show rapid and reproducible conductivity switching with up to 15\uffe2\uff80\uff90fold modulation that is restored on the application of a gate voltage. Therefore, photoactive proteins, especially GFP, can be realized as a key material for novel single\uffe2\uff80\uff90molecule electronic and photonic devices.Bionanohybrids of carbon nanotubes and fluorescent proteins (FPs) are a promising class of materials for optoelectronic applications. Understanding and controlling the charge transport mechanism between FPs and carbon nanotubes are critical to achieving functional reproducibility and exploring novel synergetic effects. This work demonstrates a novel phenomenon of photocurrent generation in field\uffe2\uff80\uff90effect transistors based on the conjugation of an individual single\uffe2\uff80\uff90walled carbon nanotube (SWCNT) and FPs. When studying the effect of gate voltage on the photoresponse, reversible switching from fast positive to a slow negative photoresponse in bionanohybrids associated with depletion and accumulation modes, respectively is observed. The latter demonstrates a stable memory effect after the light is turned off. It is revealed that in depletion mode, the charge carriers from the protein are not trapped at the interface due to effective screening by the gate potential. It is suggested that the main mechanism in photoresponse switching is a competitive effect between photogating and effective photodoping of the SWCNT by charges trapped at the nanotube interface. The noticeable effect of water molecules can support proton transfer as the main mechanism of charge transfer. This result illustrates that SWCNT/FP bionanohybrids bear great potential for the realization of novel optoelectronic devices.Strategies are provided for making robust measurements of engineered nanomaterial bioaccumulation across a broad range of organisms.
", "keywords": ["WALLED CARBON NANOTUBES", "Environmental Engineering", "Biomedical and Clinical Sciences", "TITANIUM-DIOXIDE NANOPARTICLES", "Medical Biotechnology", "ZINC-OXIDE NANOPARTICLES", "0211 other engineering and technologies", "Bioengineering", "02 engineering and technology", "PLASMA-MASS SPECTROMETRY", "SILVER NANOPARTICLES", "01 natural sciences", "Environmental Biotechnology", "ENGINEERED NANOMATERIALS", "GOLD NANOPARTICLES", "MUSSEL MYTILUS-EDULIS", "SINGLE-CELL LEVEL", "Life Science", "Generic health relevance", "Other Chemical Sciences", "PARTICLE ICP-MS", "0105 earth and related environmental sciences"]}, "links": [{"href": "http://pubs.rsc.org/en/content/articlepdf/2019/EN/C8EN01378K"}, {"href": "https://escholarship.org/content/qt3ct0979c/qt3ct0979c.pdf"}, {"href": "https://doi.org/10.1039/c8en01378k"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/Environmental%20Science%3A%20Nano", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "10.1039/c8en01378k", "name": "item", "description": "10.1039/c8en01378k", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/10.1039/c8en01378k"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2019-01-01T00:00:00Z"}}, {"id": "10.1039/d1ra03337a", "type": "Feature", "geometry": null, "properties": {"updated": "2026-04-03T16:18:49Z", "type": "Journal Article", "created": "2021-09-10", "title": "Exploring the performance of a functionalized CNT-based sensor array for breathomics through clustering and classification algorithms: from gas sensing of selective biomarkers to discrimination of chronic obstructive pulmonary disease", "description": "Extensive application of clustering and classification algorithms shows the potential of a CNT-based sensor array in breathomics.
The food industry faces numerous challenges to assure provision of tasty and convenient food that possesses extended shelf life and shows long\uffe2\uff80\uff90term high\uffe2\uff80\uff90quality preservation. Research and development of antimicrobial materials for food applications have provided active antibacterial packaging technologies that are able to meet these challenges. Furthermore, consumers expect and demand sustainable packaging materials that would reduce environmental problems associated with plastic waste. In this review, we discuss antimicrobial composite materials for active food packaging applications that combine highly efficient antibacterial nanoparticles (i.e., metal, metal oxide, mesoporous silica and graphene\uffe2\uff80\uff90based nanomaterials) with biodegradable and environmentally friendly green polymers (i.e., gelatin, alginate, cellulose, and chitosan) obtained from plants, bacteria, and animals. In addition, innovative syntheses and processing techniques used to obtain active and safe packaging are showcased. Implementation of such green active packaging can significantly reduce the risk of foodborne pathogen outbreaks, improve food safety and quality, and minimize product losses, while reducing waste and maintaining sustainability. Extensive application of clustering and classification algorithms shows the potential of a CNT-based sensor array in breathomics.
The food industry faces numerous challenges to assure provision of tasty and convenient food that possesses extended shelf life and shows long\uffe2\uff80\uff90term high\uffe2\uff80\uff90quality preservation. Research and development of antimicrobial materials for food applications have provided active antibacterial packaging technologies that are able to meet these challenges. Furthermore, consumers expect and demand sustainable packaging materials that would reduce environmental problems associated with plastic waste. In this review, we discuss antimicrobial composite materials for active food packaging applications that combine highly efficient antibacterial nanoparticles (i.e., metal, metal oxide, mesoporous silica and graphene\uffe2\uff80\uff90based nanomaterials) with biodegradable and environmentally friendly green polymers (i.e., gelatin, alginate, cellulose, and chitosan) obtained from plants, bacteria, and animals. In addition, innovative syntheses and processing techniques used to obtain active and safe packaging are showcased. Implementation of such green active packaging can significantly reduce the risk of foodborne pathogen outbreaks, improve food safety and quality, and minimize product losses, while reducing waste and maintaining sustainability.The food industry faces numerous challenges to assure provision of tasty and convenient food that possesses extended shelf life and shows long\uffe2\uff80\uff90term high\uffe2\uff80\uff90quality preservation. Research and development of antimicrobial materials for food applications have provided active antibacterial packaging technologies that are able to meet these challenges. Furthermore, consumers expect and demand sustainable packaging materials that would reduce environmental problems associated with plastic waste. In this review, we discuss antimicrobial composite materials for active food packaging applications that combine highly efficient antibacterial nanoparticles (i.e., metal, metal oxide, mesoporous silica and graphene\uffe2\uff80\uff90based nanomaterials) with biodegradable and environmentally friendly green polymers (i.e., gelatin, alginate, cellulose, and chitosan) obtained from plants, bacteria, and animals. In addition, innovative syntheses and processing techniques used to obtain active and safe packaging are showcased. Implementation of such green active packaging can significantly reduce the risk of foodborne pathogen outbreaks, improve food safety and quality, and minimize product losses, while reducing waste and maintaining sustainability.