{"type": "FeatureCollection", "features": [{"id": "10.1002/etc.4059", "type": "Feature", "geometry": null, "properties": {"updated": "2026-04-03T16:14:03Z", "type": "Journal Article", "created": "2017-12-14", "title": "Dissipative particle dynamic simulation and experimental assessment of the impacts of humic substances on aqueous aggregation and dispersion of engineered nanoparticles", "description": "Abstract \uffe2\uff80\uff83

Comprehensive experimental quantification and mapping of the aggregation and dispersion state of engineered nanoparticles (NPs) in the presence of humic substances is a great challenge. Dissipative particle dynamic (DPD) simulation was adopted to investigate the aggregation and dispersion mechanisms of NPs in the presence of a humic substance analog. Twelve different types of NPs including 2 metal-based NPs, 7 metal oxide-based NPs, and 3 carbon-based NPs in pure water (pH 3.0) and algae medium (pH 8.0) in the presence of a humic substance analogy were selected for experimental verification of the DPD simulation results. In agreement with results obtained with dynamic light scattering and phase analysis light scattering techniques, the simulations demonstrated that the presence of humic substances reduced the aggregation extent of the NPs. The DPD simulations showed that the stability and dispersity of the NPs increased first, and then decreased with increasing concentrations of humic substances. Moreover, there existed a concentration of humic substances where the NPs became more stable and more dispersed, which was experimentally verified in the case of all the NPs in the pure water and in the algae medium. Furthermore, theory and simulation indicate that both hydrophobic and hydrogen interaction play an important role in controlling the formation of NP aggregates in the presence of humic substances. Electrostatic interaction and steric repulsion are the main mechanisms underlying the effects of humic substances on the aqueous dispersion stability of NPs. Environ Toxicol Chem 2018;37:1024\uffe2\uff80\uff931031. \uffc2\uffa9 2017 SETAC

", "keywords": ["13. Climate action", "Static Electricity", "Nanoparticles", "Nanotechnology", "Water", "Computer Simulation", "14. Life underwater", "Hydrogen-Ion Concentration", "Particle Size", "Hydrophobic and Hydrophilic Interactions", "01 natural sciences", "Humic Substances", "0105 earth and related environmental sciences"]}, "links": [{"href": "https://setac.onlinelibrary.wiley.com/doi/pdf/10.1002/etc.4059"}, {"href": "https://doi.org/10.1002/etc.4059"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/Environmental%20Toxicology%20and%20Chemistry", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "10.1002/etc.4059", "name": "item", "description": "10.1002/etc.4059", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/10.1002/etc.4059"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2017-12-14T00:00:00Z"}}, {"id": "10.1016/j.cosust.2018.11.002", "type": "Feature", "geometry": null, "properties": {"updated": "2026-04-03T16:16:25Z", "type": "Journal Article", "created": "2018-11-28", "title": "Models for assessing engineered nanomaterial fate and behaviour in the aquatic environment", "description": "Engineered nanomaterials (ENMs, material containing
particles with at least one dimension less than 100 nm) are
present in a range of consumer products and could be
released into the environment from these products during
their production, use or end-of-life. The high surface to
volume ratio of nanomaterials imparts a high reactivity,
which is of interest for novel applications but may raise
concern for the environment. In the absence of
measurement methods, there is a need for modelling to
assess likely concentrations and fate arising from current
and future releases. To assess the capability that exists to
do such modelling, progress in modelling ENM fate since
2011 is reviewed. ENM-specific processes represented in
models are mainly limited to aggregation and, in some
instances, dissolution. Transformation processes (e.g.
sulphidation), the role of the manufactured coatings,
particle size distribution and particle form and state are still
usually excluded. Progress is also being made in modelling
ENMs at larger scales. Currently, models can give a
reasonable assessment of the fate of ENMs in the
environment, but a full understanding will likely require
fuller inclusion of these ENM-specific processes.", "keywords": ["RELEASE", "transformation", "aggregation", "Urbanisation", "METALLIC NANOPARTICLES", "QUANTIFICATION", "SILVER NANOPARTICLES", "01 natural sciences", "6. Clean water", "modelling", "engineered nanomaterials", "NanoFASE", "TIO2 NANOPARTICLES", "Life Science", "WATER", "NANO-SILVER", "EXPOSURE", "RISK-ASSESSMENT", "105906 Environmental geosciences", "ZINC-OXIDE", "aquatic environment", "105906 Umweltgeowissenschaften", "0105 earth and related environmental sciences"]}, "links": [{"href": "https://doi.org/10.1016/j.cosust.2018.11.002"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/Current%20Opinion%20in%20Environmental%20Sustainability", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "10.1016/j.cosust.2018.11.002", "name": "item", "description": "10.1016/j.cosust.2018.11.002", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/10.1016/j.cosust.2018.11.002"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2019-02-01T00:00:00Z"}}, {"id": "10.1016/j.biortech.2020.124095", "type": "Feature", "geometry": null, "properties": {"updated": "2026-04-03T16:16:16Z", "type": "Journal Article", "created": "2020-09-07", "title": "Biosynthesized iron sulfide nanoparticles by mixed consortia for enhanced extracellular electron transfer in a microbial fuel cell", "description": "The bioanode of mixed consortia was for the first time used to in-situ synthesize iron sulfide nanoparticles in a microbial fuel cell (MFC) over a long-term period (46\u00a0days). These poorly crystalline nanoparticles with an average size of 29.97\u00a0\u00b1\u00a07.1\u00a0nm, comprising of FeS and FeS2, significantly promoted extracellular electron transfer and thus the electricity generation of the MFC. A maximum power density of 519.00\u00a0mW/m2 was obtained from the MFC, which was 1.92 times as high as that of the control. The cell viability was promoted by a small amount of iron sulfide nanoparticles but inhibited by the thick nanoparticle 'shell' covered on the bacterial cells. Some electroactive and sulfur reducing bacteria (eg. Enterobacteriaceae, Desulfovibrio, and Geobacter) were specifically enriched on the anode. This study provides a novel insight for improving the performance of bioelectrochemical systems through in-situ sustainable nanomaterials biofabrication by mixed consortia.", "keywords": ["Electron Transport", "Electricity", "Bioelectric Energy Sources", "Nanoparticles", "Electrons", "Ferrous Compounds", "Electrodes", "7. Clean energy", "01 natural sciences", "0105 earth and related environmental sciences"], "contacts": [{"organization": "Cui, Yan, Chen, Xueru, Pan, Zhengyong, Wang, Yuqi, Xu, Qiang, Bai, Jiaying, Jia, Honghua, Zhou, Jun, Yong, Xiaoyu, Wu, Xiayuan,", "roles": ["creator"]}]}, "links": [{"href": "https://doi.org/10.1016/j.biortech.2020.124095"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/Bioresource%20Technology", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "10.1016/j.biortech.2020.124095", "name": "item", "description": "10.1016/j.biortech.2020.124095", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/10.1016/j.biortech.2020.124095"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2020-12-01T00:00:00Z"}}, {"id": "10.1016/j.chemosphere.2019.03.190", "type": "Feature", "geometry": null, "properties": {"updated": "2026-04-03T16:16:23Z", "type": "Journal Article", "created": "2019-04-01", "title": "Dissolution and aggregation kinetics of zero valent copper nanoparticles in (simulated) natural surface waters: Simultaneous effects of pH, NOM and ionic strength", "description": "The combined effects of pH, dissolved organic carbon (DOC) and Ca2+/Mg2+ on the dissolution and aggregation kinetics of zero valent copper engineered nanoparticles (Cu0 ENPs) were investigated. The dissolution and aggregation of the particles were studied in (a) synthetic aqueous media, similar in chemistry to natural surface waters, and (b) natural surface waters samples, for up to 32 or 24\u202fh. The DOC stabilized the particles and prevented aggregation, and thus increased the available surface area. The higher available surface area in turn accelerated the dissolution of the particles. The presence of Ca2+/Mg2+, however, changed the aggregation and the dissolution of the DOC-stabilized particles. The influence of Ca2+/Mg2+ on DOC-stabilized particles was different at different pH's. In the absence of DOC, 10\u202fmM of Ca2+/Mg2+ induced charge reversal on the particles and caused particle stability against aggregation. This subsequently increased particles dissolution. The results obtained with regard to dissolution and aggregation of the particles in natural surface waters were compared with those determined for the synthetic waters. This comparison showed that the behavior of the particles in the natural surface waters was mostly similar to the behavior determined for media at pH 9. Overall, the current study provides some novel insights into the simultaneous effects of physicochemical parameters of water on particle stability against aggregation and dissolution, and provides data about how the processes of aggregation and dissolution of Cu0 ENPs interact and jointly determine the overall particle fate.", "keywords": ["Cations", " Divalent", "Environmental fate", "Osmolar Concentration", "0211 other engineering and technologies", "Metal Nanoparticles", "Fresh Water", "02 engineering and technology", "Hydrogen-Ion Concentration", "01 natural sciences", "Physico-chemical parameters", "6. Clean water", "Aggregation", "Kinetics", "Solubility", "Aggregation; Complexation; Copper nanoparticles; Dissolution; Environmental fate; Natural water; Physico-chemical parameters", "Complexation", "Natural water", "Calcium", "Magnesium", "Copper nanoparticles", "Organic Chemicals", "Dissolution", "Copper", "0105 earth and related environmental sciences"]}, "links": [{"href": "https://doi.org/10.1016/j.chemosphere.2019.03.190"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/Chemosphere", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "10.1016/j.chemosphere.2019.03.190", "name": "item", "description": "10.1016/j.chemosphere.2019.03.190", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/10.1016/j.chemosphere.2019.03.190"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2019-07-01T00:00:00Z"}}, {"id": "10.1016/j.colsurfa.2018.05.091", "type": "Feature", "geometry": null, "properties": {"updated": "2026-04-03T16:16:24Z", "type": "Journal Article", "created": "2018-05-30", "title": "Protein affinity for TiO2 and CeO2 manufactured nanoparticles. From ultra-pure water to biological media", "description": "Abstract In this study, we investigated the Bovine Serum Albumin (BSA) protein affinity for manufactured metal oxide nanoparticles (NPs), respectively TiO2 and CeO2. Changes in the NPs surface charge property and resulting stability were investigated by considering pH-dependent electrostatic scenarios and contrasting solution conditions from ultra-pure water to more complex biological mixtures regarding the ionic and protein composition. After careful characterization of NPs and BSA as a function of pH, we used variable BSA concentrations to study the impact of BSA adsorption and we found that protein affinity for NPs was largely controlled by electrostatic interactions. We demonstrated that in ultra-pure water increasing gradually the BSA concentration results in aggregation when BSA and NPs charges are opposite (charge neutralization). On the other hand, when NPs were added in a solution containing BSA, aggregation was prevented due to corona formation. Then, the ultrapure water was replaced by Dulbecco\u2019s phosphate-buffered saline (DPBS) to mimic the blood composition and ionic strength. BSA was then replaced by fetal calf serum (FCS) to mimic the great variety of proteins and other biomolecules found in the blood. Our findings indicate that, in all cases, initially dispersed TiO2 or CeO2 NPs are stabilized by the presence of proteins and that protein adsorption is fast regarding NPs homoaggregation. Proteins are found to improve NPs dispersion even at high ionic strength with overarching consequences on the fate, transport and related risk of NPs in living systems.", "keywords": ["Aggregation", "info:eu-repo/classification/ddc/550", "TiO2 and CeO2", "ddc:550", "0211 other engineering and technologies", "Nanoparticles", "Protein adsorption", "02 engineering and technology", "01 natural sciences", "Protein affinity", "0105 earth and related environmental sciences"]}, "links": [{"href": "https://doi.org/10.1016/j.colsurfa.2018.05.091"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/Colloids%20and%20Surfaces%20A%3A%20Physicochemical%20and%20Engineering%20Aspects", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "10.1016/j.colsurfa.2018.05.091", "name": "item", "description": "10.1016/j.colsurfa.2018.05.091", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/10.1016/j.colsurfa.2018.05.091"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2018-09-01T00:00:00Z"}}, {"id": "10.1016/j.envpol.2016.08.044", "type": "Feature", "geometry": null, "properties": {"updated": "2026-04-03T16:16:40Z", "type": "Journal Article", "created": "2016-08-31", "title": "The role of PVP in the bioavailability of Ag from the PVP-stabilized Ag nanoparticle suspension", "description": "We assessed the bioavailability of Ag from Ag nanoparticles (NPs), stabilized with polyvinylpyrrolidone (PVP), to terrestrial isopods which were exposed to 10, 100 and 1000\u00a0\u03bcg Ag NPs/g of dry food. Different Ag species were determined in the NP suspension that was fed to isopods: (i) total Ag by atomic absorption spectroscopy, (ii) the sum of Ag-PVP complexes and free Ag+ by anodic stripping voltammetry at the bismuth-film electrode, and (iii) free Ag+ by ion-selective potentiometry. The amounts of Ag species in the consumed food were compared to the masses of Ag accumulated in the isopod digestive glands. Our results show that all three Ag species (Ag NPs, Ag-PVP complexes and free Ag+) could be the source of bioaccumulated Ag, but to various degrees depending on the exposure concentration and transformations in the digestive system. We provide a proof that (i) Ag NPs dissolve and Ag-PVP complexes dissociate in the isopod digestive tract; (ii) the concentration of free Ag+ in the suspension offered to the test organisms is not the only measure of bioavailable Ag. The type of NP stabilizer along with the NP transformations in the digestive system needs to be considered in the creation of new computational models of the nanomaterial fate.", "keywords": ["voltammetry", "Ag ions", "Silver", "Biological Availability", "Metal Nanoparticles", "Povidone", "ion-selective electrode", "02 engineering and technology", "Ag complexes", "01 natural sciences", "Gastrointestinal Tract", "terrestrial isopod", "Suspensions", "Animals", "info:eu-repo/classification/udc/620.3", "0210 nano-technology", "Isopoda", "0105 earth and related environmental sciences"]}, "links": [{"href": "https://doi.org/10.1016/j.envpol.2016.08.044"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/Environmental%20Pollution", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "10.1016/j.envpol.2016.08.044", "name": "item", "description": "10.1016/j.envpol.2016.08.044", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/10.1016/j.envpol.2016.08.044"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2016-11-01T00:00:00Z"}}, {"id": "10.1016/j.envpol.2017.12.015", "type": "Feature", "geometry": null, "properties": {"updated": "2026-04-03T16:16:41Z", "type": "Journal Article", "created": "2017-12-21", "title": "Impact of water chemistry on the behavior and fate of copper nanoparticles", "description": "A full-factorial test design was applied to systematically investigate the contribution and significance of water chemistry parameters (pH, divalent cations and dissolved organic carbon (DOC) concentration) and their interactions on the behavior and fate of copper nanoparticles (CuNPs). The total amount of Cu remaining in the water column after 48\u00a0h of incubation was mostly influenced by divalent cation content, DOC concentration and the interaction of divalent cations and DOC. DOC concentration was the predominant factor influencing the dissolution of CuNPs, which was far more important than the effect of pH in the range from 6 to 9 on the dissolution of the CuNPs. The addition of DOC at concentrations ranging from 5 to 50\u00a0mg\u00a0C/L resulted in a 3-5 fold reduction of dissolution of CuNPs after 48\u00a0h of incubation, as compared to the case without addition of DOC. Divalent cation content was found to be the most influential factor regarding aggregation behavior of the particles, followed by DOC concentration and the interaction of divalent cations and DOC. In addition, the aggregation behavior of CuNPs rather than particulate dissolution explained most of the variance in the sedimentation profiles of CuNPs. These results are meaningful for improved understanding and prediction of the behavior and fate of metallic NPs in aqueous environments.", "keywords": ["Cations", " Divalent", "0211 other engineering and technologies", "Metal Nanoparticles", "Water", "Fresh Water", "02 engineering and technology", "Hydrogen-Ion Concentration", "01 natural sciences", "Carbon", "13. Climate action", "Organic Chemicals", "Copper", "Water Pollutants", " Chemical", "Environmental Monitoring", "0105 earth and related environmental sciences"]}, "links": [{"href": "https://doi.org/10.1016/j.envpol.2017.12.015"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/Environmental%20Pollution", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "10.1016/j.envpol.2017.12.015", "name": "item", "description": "10.1016/j.envpol.2017.12.015", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/10.1016/j.envpol.2017.12.015"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2018-03-01T00:00:00Z"}}, {"id": "10.1016/j.envpol.2019.05.106", "type": "Feature", "geometry": null, "properties": {"updated": "2026-04-03T16:16:41Z", "type": "Journal Article", "created": "2019-05-21", "title": "Bioturbation of Ag2S-NPs in soil columns by earthworms", "description": "Sewage sludge contains Ag2S-NPs causing NP exposure of soil fauna when sludge is applied as soil amendment. Earthworm bioturbation is an important process affecting many soil functions. Bioturbation may be affected by the presence of Ag2S-NPs, but the earthworm activity itself may also influence the displacement of these NPs that otherwise show little transport in the soil. The aim of this study was to determine effects of Ag2S-NPs on earthworm bioturbation and effect of this bioturbation on the vertical distribution of Ag2S-NPs. Columns (12\u202fcm) of a sandy loamy soil with and without Lumbricus rubellus were prepared with and without 10\u202fmg Ag kg-1, applied as Ag2S-NPs in the top 2\u202fcm of the soil, while artificial rainwater was applied at \u223c1.2\u202fmm day-1. The soil columns were sampled at three depths weekly for 28 days and leachate collected from the bottom. Total Ag measurements showed more displacement of Ag to deeper soil layers in the columns with earthworms. The application of rain only did not significantly affect Ag transport in the soil. No Ag was detected in column leachates. X-ray tomography showed that changes in macro porosity and pore size distribution as a result of bioturbation were not different between columns with and without Ag2S-NPs. Earthworm activity was therefore not affected by Ag2S-NPs at the used exposure concentration. Ag concentrations along the columns and the earthworm density allowed the calculation of the bioturbation rate. The effect on the Ag transport in the soil shows that earthworm burrowing activity is a relevant process that must be taken into account when studying the fate of nanoparticles in soils.", "keywords": ["Silver", "Sewage", "Tomography", " X-Ray", "Transport", "Metal Nanoparticles", "earthworms", "15. Life on land", "01 natural sciences", "6. Clean water", "soil", "Soil", "13. Climate action", "bioturbation", "transport", "Earthworms", "Nanoparticles", "Animals", "Soil Pollutants", "nanoparticles", "Bioturbation", "Oligochaeta", "SDG 6 - Clean Water and Sanitation", "0105 earth and related environmental sciences"]}, "links": [{"href": "https://doi.org/10.1016/j.envpol.2019.05.106"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/Environmental%20Pollution", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "10.1016/j.envpol.2019.05.106", "name": "item", "description": "10.1016/j.envpol.2019.05.106", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/10.1016/j.envpol.2019.05.106"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2019-09-01T00:00:00Z"}}, {"id": "10.1016/j.envpol.2024.125193", "type": "Feature", "geometry": null, "properties": {"updated": "2026-04-03T16:16:42Z", "type": "Journal Article", "created": "2024-10-24", "title": "Effect of particle size on the transport of polystyrene micro- and nanoplastic particles through quartz sand under unsaturated conditions", "description": "Micro- and nanoplastics (MNPs) are contaminants of emerging concern recently found in soil ecosystems. Their presence in terrestrial environments and their migration to aquatic environments may become a risk for the health of ecosystems and, through them, of humans. Understanding the interaction between particle properties and physicochemical and hydrodynamic factors is crucial to evaluate their fate and their potential infiltration towards groundwater. This study investigates the impact of particle size on MNPs transport through sand under unsaturated conditions. Infiltration column experiments with polystyrene MNPs ranging from 120 to 10,000\u00a0nm were conducted and supported by numerical modelling to derive reactive transport parameters. Results show a significant effect of particle size on the transport of MNPs, with higher recovery values observed for smaller particles (120\u00a0nm; 95.11%) compared to larger particles (1000\u00a0nm; 71.44%). No breakthrough was observed for 10,000\u00a0nm particles, indicating a complete retention within the quartz sand matrix. DLVO theory confirmed the dominance of electrostatic repulsive forces between MNPs and sand grains, suggesting an unfavourable environment for MNPs to adhere to quartz sand. Consequently, particle retention in the sand matrix occurs predominantly by physical processes. Equilibrium sorption modelling reveals that larger particles (1000\u00a0nm) tend to be immobilized in small pores throats due to straining, resulting in lower recoveries. When they are not trapped, particles tend to travel faster through preferential flows due to a size exclusion effect, evidenced by shorter arrival times at the column outlet compared to tracers. These findings highlight the influence of particle size on the transport and retention of MNPs in quartz sand under unsaturated conditions and contribute to a better understanding of their transport dynamics and environmental fate.", "keywords": ["Microplastics", "Q Science (General)", "Quartz", "particle size", "QS Ecology", "nanoplastics", "modelling", "Sand", "Polystyrenes", "Nanoparticles", "Soil Pollutants", "Particle Size", "Plastics", "Groundwater"], "contacts": [{"organization": "Rieckhof, Cynthia, Mart\u00ednez-Hern\u00e1ndez, Virtudes, Holzbecher, Ekkehard, Meffe, Raffaella,", "roles": ["creator"]}]}, "links": [{"href": "https://doi.org/10.1016/j.envpol.2024.125193"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/Environmental%20Pollution", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "10.1016/j.envpol.2024.125193", "name": "item", "description": "10.1016/j.envpol.2024.125193", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/10.1016/j.envpol.2024.125193"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2024-01-01T00:00:00Z"}}, {"id": "10.1016/j.heliyon.2024.e41151", "type": "Feature", "geometry": null, "properties": {"updated": "2026-04-03T16:17:07Z", "type": "Journal Article", "created": "2024-12-14", "title": "Chlorotoxin-functionalized mesoporous silica nanoparticles for pH-responsive paclitaxel delivery to Glioblastoma multiforme", "description": "Glioblastoma multiforme (GBM) is a highly aggressive brain cancer associated with poor survival rates. We developed novel mesoporous silica nanoparticles (MSNs)-based nanocarriers for pH-responsive delivery of a therapeutic drug Paclitaxel (PTX) to GBM tumor cells. The pores of MSNs are loaded with PTX, which is retained by \u03b2-cyclodextrin (CD) moieties covalently linked to the pore entrances through a hydrazone linkage, which is cleavable in weakly acidic environment. Furthermore, we utilized a host-guest interaction between the adamantane and capping CD moieties to further functionalize the surface with a potential glioma-targeting oligopeptide chlorotoxin (CHX). In vitro studies in the U87 GBM cell line show decreased uptake, but increased toxicity of CHX-modified nanoparticles compared to CHX-free nanoparticles. The obtained results are promising toward development of advanced drug nanocarriers, which may target the overexpressed receptors in cancer tissues and utilize their weakly acidic environment for triggering the drug release, potentially leading to more efficient cancer treatments.", "keywords": ["Social sciences (General)", "H1-99", "Targeted drug delivery", "Q1-390", "Science (General)", "Paclitaxel", "Mesoporous silica nanoparticles", "Cyclodextrin", "Glioblastoma multiforme", "pH-responsive", "Research Article"]}, "links": [{"href": "https://doi.org/10.1016/j.heliyon.2024.e41151"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/Heliyon", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "10.1016/j.heliyon.2024.e41151", "name": "item", "description": "10.1016/j.heliyon.2024.e41151", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/10.1016/j.heliyon.2024.e41151"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2025-01-01T00:00:00Z"}}, {"id": "10.1016/j.scitotenv.2016.08.204", "type": "Feature", "geometry": null, "properties": {"updated": "2026-04-03T16:17:29Z", "type": "Journal Article", "created": "2016-09-08", "title": "Bioaccumulation of silver in Daphnia magna: Waterborne and dietary exposure to nanoparticles and dissolved silver", "description": "Silver nanoparticles (Ag-NP) are incorporated into commercial products as antimicrobial agents, which potentiate their emission to the environment. The toxicity of Ag-NP has been associated with the release of Ag ions (Ag+), which are more toxic to aquatic organisms than Ag-NP. In this study, a toxicokinetics approach was applied to compare the potential of Daphnia magna to accumulate Ag from either Ag-NP or AgNO3 through different exposure routes: a) water, b) diet and c) water and diet. A one-compartment kinetics model was applied to describe the development of Ag body concentrations over time and derive uptake (k1w; k1d) and elimination (k2) rate constants. Under water-only exposure, AgNO3 induced higher Ag uptake rate constants and bioconcentration factors when compared to Ag-NP. For dietary exposure, no differences in Ag concentrations in D. magna, along with the kinetics parameters, were found for both Ag forms. Simultaneous water and dietary exposures to Ag-NP induced higher Ag concentrations in D. magna compared to AgNO3. In this combined exposure, uptake from water explains most for the increase in Ag body concentration in D. magna for Ag-NP exposure, whereas uptake from the diet was the major contributor for the increase in Ag concentration in D. magna under AgNO3 exposure. Biomagnification was not observed for any of the exposure routes applied in this study, neither for Ag-NP nor for AgNO3.", "keywords": ["Dietary Exposure", "Silver", "Daphnia", "13. Climate action", "0211 other engineering and technologies", "Animals", "Metal Nanoparticles", "Silver Nitrate", "02 engineering and technology", "SDG 6 - Clean Water and Sanitation", "01 natural sciences", "Water Pollutants", " Chemical", "0105 earth and related environmental sciences"]}, "links": [{"href": "https://doi.org/10.1016/j.scitotenv.2016.08.204"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/Science%20of%20The%20Total%20Environment", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "10.1016/j.scitotenv.2016.08.204", "name": "item", "description": "10.1016/j.scitotenv.2016.08.204", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/10.1016/j.scitotenv.2016.08.204"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2017-01-01T00:00:00Z"}}, {"id": "10.1016/j.scitotenv.2018.09.017", "type": "Feature", "geometry": null, "properties": {"updated": "2026-04-03T16:17:30Z", "type": "Journal Article", "created": "2018-09-04", "title": "Determination of nanoparticle heteroaggregation attachment efficiencies and rates in presence of natural organic matter monomers. Monte Carlo modelling", "description": "Understanding the transformation and transport of manufactured nanoparticles (NPs) in aquatic systems remains an important issue due to their potential hazard. Once released in aquatic systems, NPs will interact with natural compounds such as suspended inorganic particles and/or natural organic matter (NOM) and heteroaggregation will control their ultimate fate. Unfortunately, systematic experimental methods to study heteroaggregation are not straightforward and still scarce. In addition, the description of heteroaggregation rate constants and attachment efficiencies is still a matter of debate since no clear definition exists. In this work, an original cluster-cluster Monte Carlo model is developed to get an insight into heteroaggregation process descriptions. A two-component system composed of NPs and NOM fulvic acid monomers is investigated by considering several water models to cover a range of (relevant) conditions from fresh to marine waters. For that purpose, homo- and hetero- individual attachment efficiencies between NPs and NOM units are adjusted (NP-NP, NOM-NOM and NP-NOM). The influence of NP/NOM ratio, NOM-NOM homoaggregation versus heteroaggregation, and surface coating effects is studied systematically. From a quantitative point of view, aggregation rate constants as well as attachment efficiencies are calculated as a function of physical time so as to characterize the individual influence of each parameter and to allow future comparison with experimental data. Heteroaggregation processes and global attachment efficiencies corresponding to several mechanisms and depending on the evolution of heteroaggregate structures all along the simulations are defined. The calculation of attachment efficiency values is found dependent on NP/NOM concentration ratios via coating effects, by the initial set of elementary attachment efficiencies and influence of homoaggregation. Marine water represents a specific case of aggregation where all particle contacts are effective. On the other hand, in 'ultrapure' and 'fresh waters', a competition between homo- and heteroaggregation occurs depending on the initial attachment efficiencies therefore indicating that a subtle change in the NP surface properties as well as in the water chemistry have a significant impact on heteroaggregation processes.", "keywords": ["SDG 14 \u2013 Leben unter Wasser", "FATE", "0211 other engineering and technologies", "02 engineering and technology", "SILVER NANOPARTICLES", "01 natural sciences", "Nanoparticle", "ddc:550", "105906 Environmental geosciences", "SDG 14 - Life Below Water", "Monte Carlo simulation", "OXIDE NANOPARTICLES", "0105 earth and related environmental sciences", "ddc:333.7-333.9", "Natural organic matter", "NANOMATERIALS", "info:eu-repo/classification/ddc/333.7-333.9", "info:eu-repo/classification/ddc/550", "Surface coating", "ENGINEERED NANOPARTICLES", "Attachment efficiency", "Nanopartide", "TITANIUM-DIOXIDE NANOPARTICLES", "TRANSPORT", "AQUATIC ENVIRONMENT", "TIO2 NANOPARTICLES", "Natural Organic Matter", "13. Climate action", "Heteroaggregation", "105906 Umweltgeowissenschaften", "DIFFUSION-LIMITED AGGREGATION"]}, "links": [{"href": "https://doi.org/10.1016/j.scitotenv.2018.09.017"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/Science%20of%20The%20Total%20Environment", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "10.1016/j.scitotenv.2018.09.017", "name": "item", "description": "10.1016/j.scitotenv.2018.09.017", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/10.1016/j.scitotenv.2018.09.017"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2019-02-01T00:00:00Z"}}, {"id": "10.1016/j.scitotenv.2018.08.176", "type": "Feature", "geometry": null, "properties": {"updated": "2026-04-03T16:17:30Z", "type": "Journal Article", "created": "2018-08-15", "title": "Heteroaggregation of CeO2 nanoparticles in presence of alginate and iron (III) oxide", "description": "When manufactured nanoparticles are released to natural waters, heteroaggregation between nanoparticles and water compounds is expected to occur and play a key role in nanoparticle fate, transport and transformation. In this work, the heteroaggregation between CeO2 nanoparticles and Fe2O3 inorganic colloids, which represent the main inorganic fraction from Lake Geneva water, is studied. The heteroaggregation processes between CeO2, Fe2O3 and alginate in multiple water samples are investigated using zeta potential and z-average diameter measurements. The kinetics of heteroaggregation of individual components as well as mixtures of CeO2 nanoparticles and Fe2O3 colloids and alginate are studied using time resolved dynamic light scattering. The global attachment efficiency (\u03b1global) is calculated using data from kinetic experiments. \u03b1global for pristine CeO2 nanoparticles varied from 0.5 to 0.7 in lake and synthetic waters and is found around 1 for pristine Fe2O3 and mixture CeO2 and Fe2O3. Our findings demonstrate that heteroaggregation is highly dependent on environmental conditions and resulting electrostatic scenarios. No heteroaggregation at pH\u202f8 between CeO2, Fe2O3 and alginate is observed in ultrapure water, because of electrostatic repulsions between negatively charged compounds. In synthetic and lake waters, the situation is opposite. Indeed, specific adsorption of divalent cations and presence of salt are found to promote heteroaggregation via cation bridging and screening effects. The kinetic experiments indicate that aggregation rate of pristine Fe2O3 is higher (89\u202fnm/min in lake water) compared to pristine CeO2 nanoparticles (50\u202fnm/min) and on the same level as mixture of CeO2 and Fe2O3 (96\u202fnm/min). Low alginate concentration, 0.25\u202fmg/L, has no effect on heteroaggregation in mixture of CeO2 and Fe2O3 in lake and synthetic waters. On the other hand, in natural water, the presence of higher alginate concentration, 2\u202fmg/L, is found to reduce the heteroaggregation rate.", "keywords": ["info:eu-repo/classification/ddc/550", "13. Climate action", "Alginate", "ddc:550", "CeO2 nanoparticles", "Fe2O3", "Heteroaggregation", "Cation adsorption", "01 natural sciences", "6. Clean water", "Lake water", "0105 earth and related environmental sciences"]}, "links": [{"href": "https://doi.org/10.1016/j.scitotenv.2018.08.176"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/Science%20of%20The%20Total%20Environment", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "10.1016/j.scitotenv.2018.08.176", "name": "item", "description": "10.1016/j.scitotenv.2018.08.176", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/10.1016/j.scitotenv.2018.08.176"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2019-01-01T00:00:00Z"}}, {"id": "10.1016/j.scitotenv.2018.09.146", "type": "Feature", "geometry": null, "properties": {"license": "Open Access", "updated": "2026-04-03T16:17:30Z", "type": "Journal Article", "created": "2018-09-11", "title": "Simultaneous stabilization of Pb and improvement of soil strength using nZVI", "description": "This study demonstrates the feasibility of nanoscale Zero-Valent Iron (nZVI) for simultaneous stabilization of Pb and improvement of soil strength via batch experiments. The soil samples were prepared using slurry and pre-consolidation method at nZVI doses of 0.2%, 1%, 5%, and 10% (by dry weight). The physicochemical and geotechnical properties of Pb-contaminated soil treated by nZVI were analyzed. The results indicate that the contamination of Pb(II) resulted in a notable reduction in the undrained shear strength of soil from 16.85\u202fkPa to 7.25\u202fkPa. As expected, the Pb in exchangeable and carbonate-bound fractions decreased significantly with the increasing doses of nZVI. Meanwhile, the undrained shear strength of Pb-contaminated soil enhanced substantially as the increase of nZVI, from 25.83\u202fkPa (0.2% nZVI treatment) to 69.33\u202fkPa (10% nZVI treatment). An abundance of bubbles, generated from the oxidation of nZVI, was recorded. The mechanisms for simultaneous stabilization of Pb and soil improvement primarily include: 1) the precipitation and transformation of Pb-/Fe-hydrated oxides on the soil particles and their induced bounding effects; 2) the increased drainage capability of soil as the occupation of nZVI aggregates and bubbles in the macropores space and 3) the lower soil density derived from the increase in microbubbles retained in the soil. This study is provided to facilitate the application of nZVI in the redevelopment of contaminated soil.", "keywords": ["Soil", "Lead", "Iron", "0211 other engineering and technologies", "Metal Nanoparticles", "Soil Pollutants", "02 engineering and technology", "TD", "01 natural sciences", "Environmental Restoration and Remediation", "6. Clean water", "0105 earth and related environmental sciences"]}, "links": [{"href": "http://wrap.warwick.ac.uk/108516/1/WRAP-simultaneous-stabiliazation-Pb-improvement-soil-strength-Geng-2018.pdf"}, {"href": "https://doi.org/10.1016/j.scitotenv.2018.09.146"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/Science%20of%20The%20Total%20Environment", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "10.1016/j.scitotenv.2018.09.146", "name": "item", "description": "10.1016/j.scitotenv.2018.09.146", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/10.1016/j.scitotenv.2018.09.146"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2019-02-01T00:00:00Z"}}, {"id": "10.1016/j.scitotenv.2023.164311", "type": "Feature", "geometry": null, "properties": {"updated": "2026-04-03T16:17:33Z", "type": "Journal Article", "created": "2023-05-20", "title": "Electroactive microorganisms synthesizing iron sulfide nanoparticles for enhanced hexavalent chromium removal in microbial fuel cells", "description": "Microbial fuel cells (MFCs) have been considered a promising technology for Cr6+ removal, but they are limited by Cr6+-reducing biocathodes with low extracellular electron transfer (EET) and poor microbial activity. In this study, three kinds of nano-FeS hybridized electrode biofilms, obtained through synchronous biosynthesis (Sy-FeS), sequential biosynthesis (Se-FeS) and cathode biosynthesis (Ca-FeS), were applied as biocathodes for Cr6+ removal in MFCs. The Ca-FeS biocathode exhibited the best performance due to the superior properties of biogenic nano-FeS (e.g., more synthetic amount, smaller particle size, better dispersion). The MFC with the Ca-FeS biocathode achieved the highest power density (42.08\u00a0\u00b1\u00a01.42\u00a0mW/m2) and Cr6+ removal efficiency (99.18\u00a0\u00b1\u00a00.1\u00a0%), which were 1.42 and 2.08 times as high as those of the MFC with the normal biocathode, respectively. The synergistic effects of nano-FeS and microorganisms enhanced the bioelectrochemical reduction of Cr6+, first realizing deep reduction of Cr6+ to Cr0 in biocathode MFCs. This significantly alleviated the cathode passivation caused by Cr3+ deposition. In addition, the hybridized nano-FeS as 'armor' layers protected the microbes from toxic attack by Cr6+, improving the biofilm physiological activity and extracellular polymeric substances (EPS) secretion. The hybridized nano-FeS as 'electron bridges' facilitated the microbial community to form a balanced, stable and syntrophic ecological structure. This study proposes a novel strategy through the cathode in-situ biosynthesis of nanomaterials to fabricate hybridized electrode biofilms with enhanced EET and microbial activity for toxic pollutant treatment in bioelectrochemical systems.", "keywords": ["Chromium", "Bioelectric Energy Sources", "Nanoparticles", "7. Clean energy", "Electrodes"], "contacts": [{"organization": "Fan, Mengjie, Zhuang, Xinglei, Gao, Zhen, Lv, Zuopeng, Dong, Weiliang, Xin, Fengxue, Chen, Yingwen, Jia, Honghua, Wu, Xiayuan,", "roles": ["creator"]}]}, "links": [{"href": "https://doi.org/10.1016/j.scitotenv.2023.164311"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/Science%20of%20The%20Total%20Environment", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "10.1016/j.scitotenv.2023.164311", "name": "item", "description": "10.1016/j.scitotenv.2023.164311", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/10.1016/j.scitotenv.2023.164311"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2023-09-01T00:00:00Z"}}, {"id": "10.1016/j.watres.2017.10.006", "type": "Feature", "geometry": null, "properties": {"updated": "2026-04-03T16:18:07Z", "type": "Journal Article", "created": "2017-10-10", "title": "Tannic acid promotes ion release of copper oxide nanoparticles: Impacts from solution pH change and complexation reactions", "description": "The increasing number of applications in which copper oxide nanoparticles (CuO NPs) are used, may lead to potential release of CuO NPs into the environment. However, the impact of natural organic matters on the behavior and fate of CuO NPs in aquatic media is still largely unknown. In this study, the dissolution and aggregation of CuO NPs under the exposure of tannic acid (TA) were monitored over a period of 72\u00a0h, with a focus on assessing the contributions of solution pH changes and complexation reactions. Results showed that the total amount of Cu2+ released from CuO NPs increased in the presence of TA especially at the highest TA concentration of 73.5\u00a0\u03bcmol/L. Although TA was observed to wrap around the CuO NPs, the aggregation of CuO NPs was not strongly influenced by TA and by the solution pH as investigated in this study. The kinetics of Cu2+ release were fitted using the modified pseudo second-order model and the rate of dissolution was assessed to be highest at TA\u00a0=\u00a014.7\u00a0\u03bcmol/L. At pH\u00a0=\u00a04, the increased H+ concentration was responsible for increased Cu2+ release, whereas the complexation reaction between Cu2+ and TA dominated at pH\u00a0=\u00a07. These findings suggested that the effects of TA on the dissolution of CuO NPs were a combination of solution pH change and complexation reaction, the relative fractions of which also depended on the solution pH. Additionally, the percentage of Cu2+ released from the CuO NPs was found to increase upon decreasing concentrations of CuO NPs. Our work helps to further understand how and to which extent natural organic matters affect the behavior and fate of CuO NPs.", "keywords": ["0211 other engineering and technologies", "Metal Nanoparticles", "Oxides", "02 engineering and technology", "Hydrogen-Ion Concentration", "01 natural sciences", "7. Clean energy", "6. Clean water", "Kinetics", "13. Climate action", "Tannins", "Copper", "Water Pollutants", " Chemical", "0105 earth and related environmental sciences"]}, "links": [{"href": "https://doi.org/10.1016/j.watres.2017.10.006"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/Water%20Research", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "10.1016/j.watres.2017.10.006", "name": "item", "description": "10.1016/j.watres.2017.10.006", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/10.1016/j.watres.2017.10.006"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2017-12-01T00:00:00Z"}}, {"id": "10.1021/acs.est.7b02944", "type": "Feature", "geometry": null, "properties": {"updated": "2026-04-03T16:18:15Z", "type": "Journal Article", "created": "2017-10-11", "title": "Novel Multi-isotope Tracer Approach To Test ZnO Nanoparticle and Soluble Zn Bioavailability in Joint Soil Exposures", "description": "Here we use two enriched stable isotopes, 68Znen and 64Znen (>99%), to prepare 68ZnO nanoparticles (NPs) and soluble 64ZnCl2. The standard LUFA 2.2 test soil was dosed with 68ZnO NPs and soluble 64ZnCl2 to 5 mg kg-1 each, plus between 0 and 95 mg kg-1 of soluble ZnCl2 with a natural isotope composition. After 0, 1, 3, 6, and 12 months of soil incubation, earthworms (Eisenia andrei) were introduced for 72 h exposures. Analyses of soils, pore waters, and earthworm tissues using multiple collector inductively coupled plasma mass spectrometry allowed the simultaneous measurement of the diagnostic 68Zn/66Zn, 64Zn/66Zn, and 68Zn/64Zn ratios, from which the three different isotopic forms of Zn were quantified. Eisenia andrei was able to regulate Zn body concentrations with no difference observed between the different total dosing concentrations. The accumulation of labeled Zn by the earthworms showed a direct relationship with the proportion of labeled to total Zn in the pore water, which increased with longer soil incubation times and decreasing soil pH. The 68Znen/64Znen ratios determined for earthworms (1.09 \u00b1 0.04), soils (1.09 \u00b1 0.02), and pore waters (1.08 \u00b1 0.02) indicate indistinguishable environmental distribution and uptake of the Zn forms, most likely due to rapid dissolution of the ZnO NPs.", "keywords": ["104002 Analytische Chemie", "550", "TRANSFORMATIONS", "FATE", "0211 other engineering and technologies", "Biological Availability", "02 engineering and technology", "01 natural sciences", "Soil", "104002 Analytical chemistry", "104023 Umweltchemie", "ENGINEERED NANOMATERIALS", "MD Multidisciplinary", "Animals", "Soil Pollutants", "105906 Environmental geosciences", "210004 Nanomaterials", "Oligochaeta", "EARTHWORM EISENIA-ANDREI", "0105 earth and related environmental sciences", "ENVIRONMENT", "104023 Environmental chemistry", "KNOWLEDGE GAPS", "[SDU.ENVI] Sciences of the Universe [physics]/Continental interfaces", " environment", "6. Clean water", "Zinc", "Nanoparticles", "Zinc Isotopes", "Zinc Oxide", "210004 Nanomaterialien", "Environmental Sciences", "105906 Umweltgeowissenschaften"]}, "links": [{"href": "https://pubs.acs.org/doi/pdf/10.1021/acs.est.7b02944"}, {"href": "https://doi.org/10.1021/acs.est.7b02944"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/Environmental%20Science%20%26amp%3B%20Technology", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "10.1021/acs.est.7b02944", "name": "item", "description": "10.1021/acs.est.7b02944", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/10.1021/acs.est.7b02944"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2017-10-26T00:00:00Z"}}, {"id": "10.1021/acs.est.9b07562", "type": "Feature", "geometry": null, "properties": {"updated": "2026-04-03T16:18:16Z", "type": "Journal Article", "created": "2020-02-24", "title": "Silver Nanoparticles Alter Soil Microbial Community Compositions and Metabolite Profiles in Unplanted and Cucumber-Planted Soils", "description": "The rapid development of nanotechnology makes the environmental impact assessment a necessity to ensure the sustainable use of engineered nanomaterials. Here, silver nanoparticles (AgNPs) at 100 mg/kg were added to soils in the absence or presence of cucumber (Cucumis sativa) plants for 60 days. The response of the soil microbial community and associated soil metabolites was investigated by 16S rRNA gene sequencing and gas chromatography-mass spectrometry (GC-MS)-based metabolomics, respectively. The results show that AgNP exposure significantly increased the soil pH in both unplanted and cucumber-planted soils. The soil bacterial community structure was altered upon Ag exposure in both soils. Several functionally significant bacterial groups, which are associated with carbon, nitrogen, and phosphorus cycling, were compromised by AgNPs in both unplanted and cucumber-planted soils. Generally, plants played a limited role in mediating the impact of AgNPs on the bacterial community. Soil metabolomic analysis showed that AgNPs altered the metabolite profile in both unplanted and cucumber-planted soils. The significantly changed metabolites are involved in sugar and amino acid-related metabolic pathways, indicating the perturbation of C and N metabolism, which is consistent with the bacterial community structure results. In addition, several fatty acids were significantly decreased upon exposure to AgNPs in both unplanted and cucumber-planted soils, suggesting the possible oxidative stress imposed on microbial cell membranes. These results provide valuable information for understanding the biological and biochemical impact of AgNP exposure on both plant species and on soil microbial communities; such understanding is needed to understand the risk posed by these materials in the environment.", "keywords": ["0301 basic medicine", "2. Zero hunger", "0303 health sciences", "Silver", "Microbiota", "Metal Nanoparticles", "15. Life on land", "6. Clean water", "Soil", "03 medical and health sciences", "13. Climate action", "RNA", " Ribosomal", " 16S", "Cucumis sativus", "Soil Microbiology"]}, "links": [{"href": "https://pubs.acs.org/doi/pdf/10.1021/acs.est.9b07562"}, {"href": "https://doi.org/10.1021/acs.est.9b07562"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/Environmental%20Science%20%26amp%3B%20Technology", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "10.1021/acs.est.9b07562", "name": "item", "description": "10.1021/acs.est.9b07562", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/10.1021/acs.est.9b07562"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2020-02-24T00:00:00Z"}}, {"id": "10.1021/acs.jafc.9b06429", "type": "Feature", "geometry": null, "properties": {"updated": "2026-04-03T16:18:16Z", "type": "Journal Article", "created": "2020-02-24", "title": "High-Throughput Screening for Engineered Nanoparticles That Enhance Photosynthesis Using Mesophyll Protoplasts", "description": "Certain engineered nanoparticles (NPs) have unique properties that have exhibited significant potential for promoting photosynthesis and enhancing crop productivity. Understanding the fundamental interactions between NPs and plants is crucial for the sustainable development of nanoenabled agriculture. Leaf mesophyll protoplasts, which maintain similar physiological response and cellular activity as intact plants, were selected as a model system to study the impact of NPs on photosynthesis. The mesophyll protoplasts isolated from spinach were cultivated with different NMs (Fe, Mn3O4, SiO2, Ag, and MoS2) dosing at 50 mg/L for 2 h under illumination. The potential maximum quantum yield and adenosine triphosphate (ATP) production of mesophyll protoplasts were significantly increased by Mn3O4 and Fe NPs (23% and 43%, respectively), and were decreased by Ag and MoS2 NPs. The mechanism for the photosynthetic enhancement by Mn3O4 and Fe is to increase the photocurrent and electron transfer rate, as revealed by photoelectrochemical measurement. GC-MS based single cell type metabolomics reveal that NPs (Fe and MoS2) altered the metabolic profiles of mesophyll cells during 2 h of illumination period. Separately, the effect of NPs exposure on photosynthesis and biomass were also conducted at the whole plant level. A strong correlation was observed with protoplast data; plant biomass was significantly increased by Mn3O4 exposure (57%) but was decreased (24%) by treatment of Ag NPs. The use of mesophyll protoplasts can be a fast and reliable tool for screening NPs to enhance photosynthesis for potential nanofertilizer use. Importantly, inclusion of a metabolic analysis can provide mechanistic toxicity data to ensure the development 'safer-by-design' nanoenabled platforms.", "keywords": ["0301 basic medicine", "2. Zero hunger", "0303 health sciences", "03 medical and health sciences", "Protoplasts", "Nanoparticles", "Photosynthesis", "Silicon Dioxide", "High-Throughput Screening Assays"]}, "links": [{"href": "https://pubs.acs.org/doi/pdf/10.1021/acs.jafc.9b06429"}, {"href": "https://doi.org/10.1021/acs.jafc.9b06429"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/Journal%20of%20Agricultural%20and%20Food%20Chemistry", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "10.1021/acs.jafc.9b06429", "name": "item", "description": "10.1021/acs.jafc.9b06429", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/10.1021/acs.jafc.9b06429"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2020-02-24T00:00:00Z"}}, {"id": "10.1038/s41467-021-23257-y", "type": "Feature", "geometry": null, "properties": {"updated": "2026-04-03T16:18:39Z", "type": "Journal Article", "created": "2021-05-31", "title": "Imaging-based spectrometer-less optofluidic biosensors based on dielectric metasurfaces for detecting extracellular vesicles", "description": "Abstract

Biosensors are indispensable tools for public, global, and personalized healthcare as they provide tests that can be used from early disease detection and treatment monitoring to preventing pandemics. We introduce single-wavelength imaging biosensors capable of reconstructing spectral shift information induced by biomarkers dynamically using an advanced data processing technique based on an optimal linear estimator. Our method achieves superior sensitivity without wavelength scanning or spectroscopy instruments. We engineered diatomic dielectric metasurfaces supporting bound states in the continuum that allows high-quality resonances with accessible near-fields by in-plane symmetry breaking. The large-area metasurface chips are configured as microarrays and integrated with microfluidics on an imaging platform for real-time detection of breast cancer extracellular vesicles encompassing exosomes. The optofluidic system has high sensing performance with nearly 70 1/RIU figure-of-merit enabling detection of on average 0.41 nanoparticle/\uffc2\uffb5m2 and real-time measurements of extracellular vesicles binding from down to 204 femtomolar solutions. Our biosensors provide the robustness of spectrometric approaches while substituting complex instrumentation with a single-wavelength light source and a complementary-metal-oxide-semiconductor camera, paving the way toward miniaturized devices for point-of-care diagnostics.Recent advances in knowledge suggest that micro- and nanoplastics pose a threat to plant health, however, the responses of plants to this stressor are not well-known. Here we examined the response of plant cell defence mechanisms to nanoparticles of commonly used plastic, polystyrene. We used plant cell cultures of widely cultivated plants, the monocots wheat and barley (Triticum aestivum L., Hordeum vulgare L.) and the dicots carrot and tomato (Daucus carota L., Solanum lycopersicum L.). We measured the activities of enzymes involved in the scavenging of reactive oxygen species and nonenzymatic antioxidants and we estimated potential damages in plant cell structures and functioning via lipid peroxidation and DNA methylation levels. Our results demonstrate that the mode of action of polystyrene nanoparticles on plant cells involves oxidative stress. However, the changes in plant defence mechanisms are dependent on plant species, exposure time and nanoplastic concentrations. In general, both monocots showed similar responses to nanoplastics, but the carrot followed more the response of monocots than a second dicot, a tomato. Higher H2O2, lipid peroxidation and lower enzyme activities scavenging H2O2 suggest that tomato cells may be more susceptible to polystyrene-induced stress. In conclusion, polystyrene nanoplastics induce oxidative stress and the response of the plant defense mechanisms involving several chain reactions leading to oxidoreductive homeostasis.Sludge treated with ENMs caused greater effects on earthworm reproduction than sludge treated with metal salts.

", "keywords": ["13. Climate action", "4. Education", "biosolids", "Eisenia fetida", "toxicity", "zinc oxide", "nanoparticles", "silver", "bioavailability", "01 natural sciences", "6. Clean water", "12. Responsible consumption", "0105 earth and related environmental sciences"]}, "links": [{"href": "http://pubs.rsc.org/en/content/articlepdf/2017/EN/C6EN00280C"}, {"href": "https://doi.org/10.1039/C6EN00280C"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/Environmental%20Science%3A%20Nano", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "10.1039/C6EN00280C", "name": "item", "description": "10.1039/C6EN00280C", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/10.1039/C6EN00280C"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2017-01-01T00:00:00Z"}}, {"id": "10.1039/c7en01139c", "type": "Feature", "geometry": null, "properties": {"updated": "2026-04-03T16:18:48Z", "type": "Journal Article", "created": "2018-08-02", "title": "Proposal for a tiered dietary bioaccumulation testing strategy for engineered nanomaterials using fish", "description": "

The scientific community has invested effort into standardising methodologies for the regulatory ecotoxicity testing of engineered nanomaterials (ENMs), but the practical requirements for bioaccumulation testing of ENMs have been given less attention.

", "keywords": ["TITANIUM-DIOXIDE NANOPARTICLES", "ISOLATED-PERFUSED INTESTINE", "ZINC-OXIDE NANOPARTICLES", "RAINBOW-TROUT", "ZEBRAFISH DANIO-RERIO", "IN-VITRO", "3. Good health", "TROUT ONCORHYNCHUS-MYKISS", "DAPHNIA-MAGNA", "WATERBORNE COPPER NANOPARTICLES", "13. Climate action", "ECOTOXICITY TEST METHODS", "105906 Environmental geosciences", "14. Life underwater", "105906 Umweltgeowissenschaften"]}, "links": [{"href": "http://pubs.rsc.org/en/content/articlepdf/2018/EN/C7EN01139C"}, {"href": "https://doi.org/10.1039/c7en01139c"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/Environmental%20Science%3A%20Nano", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "10.1039/c7en01139c", "name": "item", "description": "10.1039/c7en01139c", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/10.1039/c7en01139c"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2018-01-01T00:00:00Z"}}, {"id": "10.1039/c8an01387j", "type": "Feature", "geometry": null, "properties": {"updated": "2026-04-03T16:18:48Z", "type": "Journal Article", "created": "2018-10-19", "title": "The in vivo effects of silver nanoparticles on terrestrial isopods, Porcellio scaber , depend on a dynamic interplay between shape, size and nanoparticle dissolution properties", "description": "

The effects of exposure to low concentrations of AgNPs in model tissue, are the result of the interplay between size, shape and dissolution of ions from NPs.

", "keywords": ["[PHYS]Physics [physics]", "Male", "0301 basic medicine", "570", "Microscopy", "Principal Component Analysis", "Silver", "Metal Nanoparticles", "540", "01 natural sciences", "03 medical and health sciences", "Solubility", "Spectroscopy", " Fourier Transform Infrared", "Animals", "Female", "Intestinal Mucosa", "Particle Size", "Isopoda", "0105 earth and related environmental sciences"]}, "links": [{"href": "http://pubs.rsc.org/en/content/articlepdf/2019/AN/C8AN01387J"}, {"href": "https://doi.org/10.1039/c8an01387j"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/The%20Analyst", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "10.1039/c8an01387j", "name": "item", "description": "10.1039/c8an01387j", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/10.1039/c8an01387j"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2019-01-01T00:00:00Z"}}, {"id": "10.1039/c8en01378k", "type": "Feature", "geometry": null, "properties": {"updated": "2026-04-03T16:18:49Z", "type": "Journal Article", "created": "2019-04-15", "title": "Strategies for robust and accurate experimental approaches to quantify nanomaterial bioaccumulation across a broad range of organisms", "description": "

Strategies are provided for making robust measurements of engineered nanomaterial bioaccumulation across a broad range of organisms.

", "keywords": ["WALLED CARBON NANOTUBES", "Environmental Engineering", "Biomedical and Clinical Sciences", "TITANIUM-DIOXIDE NANOPARTICLES", "Medical Biotechnology", "ZINC-OXIDE NANOPARTICLES", "0211 other engineering and technologies", "Bioengineering", "02 engineering and technology", "PLASMA-MASS SPECTROMETRY", "SILVER NANOPARTICLES", "01 natural sciences", "Environmental Biotechnology", "ENGINEERED NANOMATERIALS", "GOLD NANOPARTICLES", "MUSSEL MYTILUS-EDULIS", "SINGLE-CELL LEVEL", "Life Science", "Generic health relevance", "Other Chemical Sciences", "PARTICLE ICP-MS", "0105 earth and related environmental sciences"]}, "links": [{"href": "http://pubs.rsc.org/en/content/articlepdf/2019/EN/C8EN01378K"}, {"href": "https://escholarship.org/content/qt3ct0979c/qt3ct0979c.pdf"}, {"href": "https://doi.org/10.1039/c8en01378k"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/Environmental%20Science%3A%20Nano", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "10.1039/c8en01378k", "name": "item", "description": "10.1039/c8en01378k", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/10.1039/c8en01378k"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2019-01-01T00:00:00Z"}}, {"id": "10.1039/d1en00264c", "type": "Feature", "geometry": null, "properties": {"updated": "2026-04-03T16:18:49Z", "type": "Journal Article", "created": "2021-06-11", "title": "Dissolution-based uptake of CeO2nanoparticles by freshwater shrimp \u2013 a dual-radiolabelling study of the fate of anthropogenic cerium in water organisms", "description": "

A dual radiolabelling strategy was used to track CeO2NPs in freshwater shrimp showing a dissolution-based uptake pathway of cerium.

", "keywords": ["0301 basic medicine", "03 medical and health sciences", "CeO2 nanoparticles", "Uptake", "Dissoltution", "01 natural sciences", "radiolabelling", "6. Clean water", "0105 earth and related environmental sciences"]}, "links": [{"href": "https://www.hzdr.de/publications/PublDoc-19575.pdf"}, {"href": "http://pubs.rsc.org/en/content/articlepdf/2021/EN/D1EN00264C"}, {"href": "https://doi.org/10.1039/d1en00264c"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/Environmental%20Science%3A%20Nano", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "10.1039/d1en00264c", "name": "item", "description": "10.1039/d1en00264c", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/10.1039/d1en00264c"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2021-01-01T00:00:00Z"}}, {"id": "10.1080/17435390.2025.2453576", "type": "Feature", "geometry": null, "properties": {"updated": "2026-04-03T16:19:25Z", "type": "Journal Article", "created": "2025-01-22", "title": "Probing the effects of dextran-coated CeO 2 nanoparticles on lung fibroblasts using multivariate single-cell Raman spectroscopy", "description": "In this study, we investigated the cytotoxic effect of highly soluble dextran-coated CeO2 nanoparticles on human fetal lung fibroblasts MRC-5. We examined individual nanoparticle-treated cells by Raman spectroscopy and analyzed Raman spectra using non-negative principal component analysis and k-means clustering. In this way, we determined dose-dependent differences between treated cells, which were reflected through the intensity change of lipid, phospholipid and RNA-related Raman modes. Performing standard biological tests for cell growth, viability and induction of apoptosis in parallel, these changes were correlated with nanoparticle-induced apoptotic processes. The cells with specific spectral characteristics, referring to non-apoptotic, but possibly autophagic cell death modality, were also detected. Additionally, Raman imaging combined with principal component and vertex component analysis was used to map the spatial distribution of biological molecules in treated and untreated cells. This work provided the description of different resulting states of the treated cells depending on the dextran-coated CeO2 nanoparticles dose, which can be later used in the design of the nanoparticles for industrial or medical applications. The wide content of information resulting from single-cell Raman spectroscopy has the potential to detect biochemical changes caused by nanoparticles that would otherwise require a series of expensive and time-consuming standard biological techniques.", "keywords": ["PCA", "Principal Component Analysis", "Cell Survival", "Metal Nanoparticles", "Dextrans", "Apoptosis", "Cerium", "Fibroblasts", "Spectrum Analysis", " Raman", "VCA", "Cell Line", "Raman spectroscopy", "MRC-5 fibroblasts", "Humans", "Nanoparticles", "Single-Cell Analysis", "Lung", "CeO2"], "contacts": [{"organization": "Mi\u0107evi\u0107, Mirjana, Sonja, \u0106alija, Koricanac, Lela, \u017dakula, Jelena, Viloti\u0107, Aleksandra, Radovic, Marko, Golic, Igor, Korac, Aleksandra, Nacka-Aleksi\u0107, Mirjana, Stojadinovic, Bojan, Doh\u010devi\u0107-Mitrovi\u0107, Zorana,", "roles": ["creator"]}]}, "links": [{"href": "https://doi.org/10.1080/17435390.2025.2453576"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/Nanotoxicology", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "10.1080/17435390.2025.2453576", "name": "item", "description": "10.1080/17435390.2025.2453576", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/10.1080/17435390.2025.2453576"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2025-01-02T00:00:00Z"}}, {"id": "10.1088/1757-899X/364/1/012073", "type": "Feature", "geometry": null, "properties": {"updated": "2026-04-03T16:19:29Z", "type": "Journal Article", "created": "2018-06-18", "title": "Photocatalytic hydroxyapatite-titania nanocomposites for preventive conservation of marble", "description": "Soiling of external surfaces is an increasing issue for conservation of architectural heritage. Providing architectural surfaces with self-cleaning ability is one of the most promising routes of preventive conservation. To this aim, several methods have been proposed in the literature, based on the use of photocatalytic TiO2 nanoparticles, either directly applied onto the surfaces or incorporated in protective coatings. However, when nano-TiO2 is directly applied onto architectural surfaces, the particles are easily removed by rain. When TiO2 is incorporated in polymeric coatings, durability issues arise as well, because the photoactivity of TiO2 nanoparticles can promote degradation of the polymer. Here, we present an innovative alternative method, based on combination of TiO2 nanoparticles and hydroxyapatite (HAP). The incorporation of nano-TiO2 into an HAP coating protects the nanoparticles from leaching by rain, thanks to the chemical bonding between TiO2 and HAP, without diminishing their photoactivity. As a result, marble treated with HAP-TiO2 composites exhibits high self-cleaning ability and high durability, with results superior to those achieve by direct application of nano-TiO2 onto the surface, as frequently performed on site.", "keywords": ["Durability; Hydroxyapatite; Marble; Nanoparticles; Protective coatings; Rain", "02 engineering and technology", "ING-IND/22 Scienza e tecnologia dei materiali", "Soiling; Photocatalytic activity; Selfcleaning; Titanium dioxide; Hydroxyapatite; Calcium phosphate; Durability; Leaching", "IOP Conference Series: Materials Science and Engineering", "0210 nano-technology", "01 natural sciences", "0104 chemical sciences"]}, "links": [{"href": "https://cris.unibo.it/bitstream/11585/643036/1/Sassoni%20et%20al%20%282018%29%20Photocatalytic%20HAP-TiO2%20nano-composites.pdf"}, {"href": "https://doi.org/10.1088/1757-899X/364/1/012073"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/IOP%20Conference%20Series%3A%20Materials%20Science%20and%20Engineering", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "10.1088/1757-899X/364/1/012073", "name": "item", "description": "10.1088/1757-899X/364/1/012073", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/10.1088/1757-899X/364/1/012073"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2018-06-01T00:00:00Z"}}, {"id": "10.1093/toxsci/kfae051", "type": "Feature", "geometry": null, "properties": {"updated": "2026-04-03T16:19:34Z", "type": "Journal Article", "created": "2024-04-18", "title": "Parameter grouping and co-estimation in physiologically based kinetic models using genetic algorithms", "description": "Abstract

Physiologically based kinetic (PBK) models are widely used in pharmacology and toxicology for predicting the internal disposition of substances upon exposure, voluntarily or not. Due to their complexity, a large number of model parameters need to be estimated, either through in silico tools, in vitro experiments, or by fitting the model to in vivo data. In the latter case, fitting complex structural models on in vivo data can result in overparameterization and produce unrealistic parameter estimates. To address these issues, we propose a novel parameter grouping approach, which reduces the parametric space by co-estimating groups of parameters across compartments. Grouping of parameters is performed using genetic algorithms and is fully automated, based on a novel goodness-of-fit metric. To illustrate the practical application of the proposed methodology, two case studies were conducted. The first case study demonstrates the development of a new PBK model, while the second focuses on model refinement. In the first case study, a PBK model was developed to elucidate the biodistribution of titanium dioxide (TiO2) nanoparticles in rats following intravenous injection. A variety of parameter estimation schemes were employed. Comparative analysis based on goodness-of-fit metrics demonstrated that the proposed methodology yields models that outperform standard estimation approaches, while utilizing a reduced number of parameters. In the second case study, an existing PBK model for perfluorooctanoic acid (PFOA) in rats was extended to incorporate additional tissues, providing a more comprehensive portrayal of PFOA biodistribution. Both models were validated through independent in vivo studies to ensure their reliability.The food industry faces numerous challenges to assure provision of tasty and convenient food that possesses extended shelf life and shows long\uffe2\uff80\uff90term high\uffe2\uff80\uff90quality preservation. Research and development of antimicrobial materials for food applications have provided active antibacterial packaging technologies that are able to meet these challenges. Furthermore, consumers expect and demand sustainable packaging materials that would reduce environmental problems associated with plastic waste. In this review, we discuss antimicrobial composite materials for active food packaging applications that combine highly efficient antibacterial nanoparticles (i.e., metal, metal oxide, mesoporous silica and graphene\uffe2\uff80\uff90based nanomaterials) with biodegradable and environmentally friendly green polymers (i.e., gelatin, alginate, cellulose, and chitosan) obtained from plants, bacteria, and animals. In addition, innovative syntheses and processing techniques used to obtain active and safe packaging are showcased. Implementation of such green active packaging can significantly reduce the risk of foodborne pathogen outbreaks, improve food safety and quality, and minimize product losses, while reducing waste and maintaining sustainability.

Mesoporous silica nanoparticles (MSNs) exhibit highly beneficial characteristics for devising efficient biosensors for different analytes. Their unique properties, such as capabilities for stable covalent binding to recognition groups (e.g., antibodies or aptamers) and sensing surfaces, open a plethora of opportunities for biosensor construction. In addition, their structured porosity offers capabilities for entrapping signaling molecules (dyes or electroactive species), which could be released efficiently in response to a desired analyte for effective optical or electrochemical detection. This work offers an overview of recent research studies (in the last five years) that contain MSNs in their optical and electrochemical sensing platforms for the detection of cancer biomarkers, classified by cancer type. In addition, this study provides an overview of cancer biomarkers, as well as electrochemical and optical detection methods in general.

", "keywords": ["MSNs", "cancer biomarkers", "Review", "Biosensing Techniques", "Electrochemical Techniques", "02 engineering and technology", "biosensors", "optical detection", "Silicon Dioxide", "01 natural sciences", "0104 chemical sciences", "3. Good health", "Neoplasms", "electrochemical detection", "Biomarkers", " Tumor", "Nanoparticles", "Humans", "0210 nano-technology", "Porosity", "TP248.13-248.65", "Biotechnology"]}, "links": [{"href": "https://www.mdpi.com/2079-6374/14/7/326/pdf"}, {"href": "https://doi.org/10.3390/bios14070326"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/Biosensors", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "10.3390/bios14070326", "name": "item", "description": "10.3390/bios14070326", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/10.3390/bios14070326"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2024-06-30T00:00:00Z"}}, {"id": "10.3390/ma11060957", "type": "Feature", "geometry": null, "properties": {"updated": "2026-04-03T16:22:35Z", "type": "Journal Article", "created": "2018-06-05", "title": "The Biological Fate of Silver Nanoparticles from a Methodological Perspective", "description": "

We analyzed the performance and throughput of currently available analytical techniques for quantifying body burden and cell internalization/distribution of silver nanoparticles (Ag NPs). Our review of Ag NP biological fate data shows that most of the evidence gathered for Ag NPs body burden actually points to total Ag and not only Ag NPs. On the other hand, Ag NPs were found inside the cells and tissues of some organisms, but comprehensive explanation of the mechanism(s) of NP entry and/or in situ formation is usually lacking. In many cases, the methods used to detect NPs inside the cells could not discriminate between ions and particles. There is currently no single technique that would discriminate between the metals species, and at the same time enable localization and quantification of NPs down to the cellular level. This paper serves as an orientation towards selection of the appropriate method for studying the fate of Ag NPs in line with their properties and the specific question to be addressed in the study. Guidance is given for method selection for quantification of NP uptake, biodistribution, precise tissue and cell localization, bioaccumulation, food chain transfer and modeling studies regarding the optimum combination of methods and key factors to consider.

", "keywords": ["0301 basic medicine", "2. Zero hunger", "spectroscopy", "Review", "01 natural sciences", "quantification", "body burden", "internalization", "03 medical and health sciences", "bioaccumulation", "microscopy", "silver nanoparticles review", "info:eu-repo/classification/udc/620.3", "biodistribution", "throughput", "performance", "0105 earth and related environmental sciences"]}, "links": [{"href": "http://www.mdpi.com/1996-1944/11/6/957/pdf"}, {"href": "https://doi.org/10.3390/ma11060957"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/Materials", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "10.3390/ma11060957", "name": "item", "description": "10.3390/ma11060957", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/10.3390/ma11060957"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2018-06-05T00:00:00Z"}}, {"id": "10.3390/nano11010080", "type": "Feature", "geometry": null, "properties": {"updated": "2026-04-03T16:22:38Z", "type": "Journal Article", "created": "2021-01-04", "title": "Laser-Tunable Printed ZnO Nanoparticles for Paper-Based UV Sensors with Reduced Humidity Interference.", "description": "

Development of paper-based sensors that do not suffer with humidity interference is desirable for practical environmental applications. In this work, a laser processing method was reported to effectively modulate the cross-sensitivity to humidity of ZnO-based UV (Ultraviolet) sensors printed on paper substrate. The results reveal that the laser induced zinc oxide (ZnO) surface morphology contributes to the super-hydrophobicity of the printed ZnO nanoparticles, reducing humidity interference while enhancing UV sensitivity. Herein, this conducted research highlights for the first time that laser processing is an attractive choice that reduces the cross-sensitivity to water vapor in the UV sensing response of ZnO-based devices printed on paper, paving the way to low-cost and sophisticated paper-based sensors.

", "keywords": ["humidity resistance", "Chemistry", "13. Climate action", "ZnO nanoparticles", "UV sensors", "paper-based device", "02 engineering and technology", "0210 nano-technology", "QD1-999", "paper-based device; UV sensors; ZnO nanoparticles; humidity resistance", "Article"]}, "links": [{"href": "http://www.mdpi.com/2079-4991/11/1/80/pdf"}, {"href": "https://www.mdpi.com/2079-4991/11/1/80/pdf"}, {"href": "https://doi.org/10.3390/nano11010080"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/Nanomaterials", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "10.3390/nano11010080", "name": "item", "description": "10.3390/nano11010080", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/10.3390/nano11010080"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2021-01-02T00:00:00Z"}}, {"id": "10.3390/pharmaceutics13040460", "type": "Feature", "geometry": null, "properties": {"updated": "2026-04-03T16:22:38Z", "type": "Journal Article", "created": "2021-03-29", "title": "pH-Responsive Release of Ruthenium Metallotherapeutics from Mesoporous Silica-Based Nanocarriers", "description": "

Ruthenium complexes are attracting interest in cancer treatment due to their potent cytotoxic activity. However, as their high toxicity may also affect healthy tissues, efficient and selective drug delivery systems to tumour tissues are needed. Our study focuses on the construction of such drug delivery systems for the delivery of cytotoxic Ru(II) complexes upon exposure to a weakly acidic environment of tumours. As nanocarriers, mesoporous silica nanoparticles (MSN) are utilized, whose surface is functionalized with two types of ligands, (2-thienylmethyl)hydrazine hydrochloride (H1) and (5,6-dimethylthieno[2,3-d]pyrimidin-4-yl)hydrazine (H2), which were attached to MSN through a pH-responsive hydrazone linkage. Further coordination to ruthenium(II) center yielded two types of nanomaterials MSN-H1[Ru] and MSN-H2[Ru]. Spectrophotometric measurements of the drug release kinetics at different pH (5.0, 6.0 and 7.4) confirm the enhanced release of Ru(II) complexes at lower pH values, which is further supported by inductively coupled plasma optical emission spectrometry (ICP-OES) measurements. Furthermore, the cytotoxicity effect of the released metallotherapeutics is evaluated in vitro on metastatic B16F1 melanoma cells and enhanced cancer cell-killing efficacy is demonstrated upon exposure of the nanomaterials to weakly acidic conditions. The obtained results showcase the promising capabilities of the designed MSN nanocarriers for the pH-responsive delivery of metallotherapeutics and targeted treatment of cancer.

", "keywords": ["Ruthenium-based anti-cancer drugs", "ruthenium-based anticancer drugs", "PH-responsive drug delivery", "Mesoporous silica nanoparticles", "pH-responsive drug delivery", "02 engineering and technology", "controlled drug delivery", "01 natural sciences", "Article", "cancer treatment", "ddc:", "3. Good health", "0104 chemical sciences", "RS1-441", "Pharmacy and materia medica", "Cancer treatment", "mesoporous silica nanoparticles", "0210 nano-technology", "Controlled drug delivery"]}, "links": [{"href": "http://www.mdpi.com/1999-4923/13/4/460/pdf"}, {"href": "https://www.mdpi.com/1999-4923/13/4/460/pdf"}, {"href": "https://doi.org/10.3390/pharmaceutics13040460"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/Pharmaceutics", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "10.3390/pharmaceutics13040460", "name": "item", "description": "10.3390/pharmaceutics13040460", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/10.3390/pharmaceutics13040460"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2021-03-28T00:00:00Z"}}, {"id": "10.3390/plants9121804", "type": "Feature", "geometry": null, "properties": {"updated": "2026-04-03T16:22:39Z", "type": "Journal Article", "created": "2020-12-21", "title": "Genotype \u00d7 Environment Interaction for Wheat Yield Traits Suitable for Selection in Different Seed Priming Conditions", "description": "

Different seed priming treatments are widely used in order to improve the nutritional status of wheat, as well as to improve its grain yield and yield- related traits. The present study aimed to evaluate the impact of seed priming with zinc oxide nanoparticles (ZnO NPs) on the yield related traits, such as, field emergence, plant height, spike length and grain yield per plant of four winter wheat genotypes (Triticum aestivum L.) during two vegetation seasons of 2018/2019 and 2019/2020. The seeds of each wheat genotypes were primed with different concentrations of ZnO NPs (0 mg L\u22121, 10 mg L\u22121, 100 mg L\u22121 and 1000 mg L\u22121) for 48 h in a dark box by continuous aeration and were sown in soil pots with 60\u201370% moisture content until full maturity. The additive main effects and multiplicative interaction (AMMI) models were used to study the genotype environment effects. The results indicated that the plants response to ZnO nanoparticles significantly increased all of the observed traits of the wheat, while its maximum rates reduced the traits of the wheat. The AMMI analysis revealed the very complex nature of the variation observed in the trial and showed the significant effect of the G\u00d7E interaction, in which the first main component was significant for all components.

", "keywords": ["0106 biological sciences", "2. Zero hunger", "wheat;\u00a0zinc oxide nanoparticles;\u00a0GEI;\u00a0AMMI", "AMMI", "GEI", "Botany", "zinc oxide nanoparticles", "Ammi", "Vegetation", "04 agricultural and veterinary sciences", "15. Life on land", "01 natural sciences", "Article", "Seed priming", "Horticulture", "13. Climate action", "wheat", "QK1-989", "Grain yield", "0401 agriculture", " forestry", " and fisheries", "Multiplicative interaction", "Gene\u2013environment interaction", "Aeration", "Water content"]}, "links": [{"href": "http://www.mdpi.com/2223-7747/9/12/1804/pdf"}, {"href": "https://www.mdpi.com/2223-7747/9/12/1804/pdf"}, {"href": "https://doi.org/10.3390/plants9121804"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/Plants", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "10.3390/plants9121804", "name": "item", "description": "10.3390/plants9121804", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/10.3390/plants9121804"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2020-12-19T00:00:00Z"}}, {"id": "10.3390/s17030516", "type": "Feature", "geometry": null, "properties": {"updated": "2026-04-03T16:22:44Z", "type": "Journal Article", "created": "2017-03-09", "title": "Humidity Sensing Properties of Paper Substrates and Their Passivation with ZnO Nanoparticles for Sensor Applications", "description": "

In this paper, we investigated the effect of humidity on paper substrates and propose a simple and low-cost method for their passivation using ZnO nanoparticles. To this end, we built paper-based microdevices based on an interdigitated electrode (IDE) configuration by means of a mask-less laser patterning method on simple commercial printing papers. Initial resistive measurements indicate that a paper substrate with a porous surface can be used as a cost-effective, sensitive and disposable humidity sensor in the 20% to 70% relative humidity (RH) range. Successive spin-coated layers of ZnO nanoparticles then, control the effect of humidity. Using this approach, the sensors become passive to relative humidity changes, paving the way to the development of ZnO-based gas sensors on paper substrates insensitive to humidity.

", "keywords": ["paper substrate", "disposable sensors", "ZnO nanoparticles", "Chemical technology", "TP1-1185", "02 engineering and technology", "0210 nano-technology", "humidity passivation; paper substrate; ZnO nanoparticles; disposable sensors", "Article", "humidity passivation"]}, "links": [{"href": "http://www.mdpi.com/1424-8220/17/3/516/pdf"}, {"href": "https://doi.org/10.3390/s17030516"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/Sensors", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "10.3390/s17030516", "name": "item", "description": "10.3390/s17030516", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/10.3390/s17030516"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2017-03-04T00:00:00Z"}}, {"id": "10.3390/s17081854", "type": "Feature", "geometry": null, "properties": {"updated": "2026-04-03T16:22:44Z", "type": "Journal Article", "created": "2017-08-11", "title": "Fabrication and Characterization of Flexible and Miniaturized Humidity Sensors Using Screen-Printed TiO2 Nanoparticles as Sensitive Layer", "description": "

This paper describes the fabrication and the characterization of an original example of a miniaturized resistive-type humidity sensor, printed on flexible substrate in a large-scale manner. The fabrication process involves laser ablation for the design of interdigitated electrodes on PET (Poly-Ethylene Terephthalate) substrate and a screen-printing process for the deposition of the sensitive material, which is based on TiO2 nanoparticles. The laser ablation process was carefully optimized to obtain micro-scale and well-resolved electrodes on PET substrate. A functional paste based on cellulose was prepared in order to allow the precise screen-printing of the TiO2 nanoparticles as sensing material on the top of the electrodes. The current against voltage (I\u2013V) characteristic of the sensor showed good linearity and potential for low-power operation. The results of a humidity-sensing investigation and mechanical testing showed that the fabricated miniaturized sensors have excellent mechanical stability, sensing characteristics, good repeatability, and relatively fast response/recovery times operating at room temperature.

", "keywords": ["flexible substrate", "Chemical technology", "laser ablation", "humidity sensors", "TP1-1185", "02 engineering and technology", "0210 nano-technology", "TiO2 nanoparticles", "screen-printing", "humidity sensors; flexible substrate; TiO2 nanoparticles; screen-printing; laser ablation", "Article"]}, "links": [{"href": "http://www.mdpi.com/1424-8220/17/8/1854/pdf"}, {"href": "https://doi.org/10.3390/s17081854"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/Sensors", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "10.3390/s17081854", "name": "item", "description": "10.3390/s17081854", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/10.3390/s17081854"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2017-08-11T00:00:00Z"}}, {"id": "10.5281/zenodo.14639137", "type": "Feature", "geometry": null, "properties": {"license": "unspecified", "updated": "2026-04-03T16:24:33Z", "type": "Dataset", "title": "Data: Natural nanoparticles and colloids in forested streams across Europe: seasonal patterns and impact of soil groups", "description": "Data and R codes for Manuscript:\u00a0 The element loss from forested ecosystems is largely reflected by the so-called dissolved phase (< 450 nm) in stream waters. However, natural colloids (1 nm \u2013 1 \u00b5m), including natural nanoparticles (NNP, 1-100 nm), constitute a major but so far, largely unexplored part of this dissolved phase. We hypothesized that i) there is a systematic seasonal variation in colloidal concentrations across European catchments, and, that ii) the colloidal concentrations are mainly controlled by site conditions, i.e., prevalent reference soil groups. To test these hypotheses, the base flow of seven stream waters was sampled from a transect across Europe from Northern Finland to Portugal at monthly intervals for one year. Three colloidal size fractions (1-20 nm, >20-60 nm and >60 nm) were identified using Field Flow Fractionation coupled with inductively coupled plasma mass spectrometry and an organic carbon detector for the size-resolved detection of Al, Si, P, Ca, Mg, Mn, Fe, Zn and organic C. Colloids accounted for up to 90-100% of total element concentrations, emphasizing the importance of colloids for element cycling. Element concentrations showed seasonal patterns in stream waters. These patterns, however, differed between the catchments with distinct soil groups: the catchments with dystrophic terrestrial soils exhibited peak flows in colloidal element concentrations during spring, while those with eutrophic terrestrial soils did during summer. By contrast, catchments with semiterrestrial soils showed season-unrelated, single peaks of high element export. Peak concentrations were also influenced by the climatic regime, which in turn impacted colloid abundance.", "keywords": ["forests", "colloids", "nanoparticles", "europe", "soil"], "contacts": [{"organization": "Schimmel, Heike, Amelung, Wulf, Braun, Melanie,", "roles": ["creator"]}]}, "links": [{"href": "https://doi.org/10.5281/zenodo.14639137"}, {"rel": "self", "type": "application/geo+json", "title": "10.5281/zenodo.14639137", "name": "item", "description": "10.5281/zenodo.14639137", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/10.5281/zenodo.14639137"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2025-01-13T00:00:00Z"}}, {"id": "10.5281/zenodo.4655380", "type": "Feature", "geometry": null, "properties": {"updated": "2026-04-03T16:25:20Z", "type": "Journal Article", "created": "2021-03-29", "title": "pH-Responsive Release of Ruthenium Metallotherapeutics from Mesoporous Silica-Based Nanocarriers.", "description": "

Ruthenium complexes are attracting interest in cancer treatment due to their potent cytotoxic activity. However, as their high toxicity may also affect healthy tissues, efficient and selective drug delivery systems to tumour tissues are needed. Our study focuses on the construction of such drug delivery systems for the delivery of cytotoxic Ru(II) complexes upon exposure to a weakly acidic environment of tumours. As nanocarriers, mesoporous silica nanoparticles (MSN) are utilized, whose surface is functionalized with two types of ligands, (2-thienylmethyl)hydrazine hydrochloride (H1) and (5,6-dimethylthieno[2,3-d]pyrimidin-4-yl)hydrazine (H2), which were attached to MSN through a pH-responsive hydrazone linkage. Further coordination to ruthenium(II) center yielded two types of nanomaterials MSN-H1[Ru] and MSN-H2[Ru]. Spectrophotometric measurements of the drug release kinetics at different pH (5.0, 6.0 and 7.4) confirm the enhanced release of Ru(II) complexes at lower pH values, which is further supported by inductively coupled plasma optical emission spectrometry (ICP-OES) measurements. Furthermore, the cytotoxicity effect of the released metallotherapeutics is evaluated in vitro on metastatic B16F1 melanoma cells and enhanced cancer cell-killing efficacy is demonstrated upon exposure of the nanomaterials to weakly acidic conditions. The obtained results showcase the promising capabilities of the designed MSN nanocarriers for the pH-responsive delivery of metallotherapeutics and targeted treatment of cancer.

", "keywords": ["Ruthenium-based anti-cancer drugs", "ruthenium-based anticancer drugs", "PH-responsive drug delivery", "Mesoporous silica nanoparticles", "pH-responsive drug delivery", "02 engineering and technology", "controlled drug delivery", "01 natural sciences", "Article", "cancer treatment", "ddc:", "3. Good health", "0104 chemical sciences", "RS1-441", "Pharmacy and materia medica", "Cancer treatment", "mesoporous silica nanoparticles", "0210 nano-technology", "Controlled drug delivery"]}, "links": [{"href": "http://www.mdpi.com/1999-4923/13/4/460/pdf"}, {"href": "https://www.mdpi.com/1999-4923/13/4/460/pdf"}, {"href": "https://doi.org/10.5281/zenodo.4655380"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/Pharmaceutics", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "10.5281/zenodo.4655380", "name": "item", "description": "10.5281/zenodo.4655380", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/10.5281/zenodo.4655380"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2021-03-28T00:00:00Z"}}, {"id": "21.15107/rcub_cer_4573", "type": "Feature", "geometry": null, "properties": {"updated": "2026-04-03T16:27:53Z", "type": "Dataset", "title": "Supplementary material to: \"Ph-responsive release of ruthenium metallotherapeutics from mesoporous silica-based nanocarriers\"", "description": "Open AccessPublished version of the article: [https://cer.ihtm.bg.ac.rs/handle/123456789/4572]", "keywords": ["Ruthenium-based anti-cancer drugs", "PH-responsive drug delivery", "Cancer treatment", "Mesoporous silica nanoparticles", "Controlled drug delivery"], "contacts": [{"organization": "Mladenovi\u0107, Minja, Morgan, Ibrahim, Ili\u0107, Neboj\u0161a, Saoud, Mohamad, Pergal, Marija, Kalu\u0111erovi\u0107, Goran N., Kne\u017eevi\u0107, Nikola \u017d.,", "roles": ["creator"]}]}, "links": [{"href": "https://doi.org/21.15107/rcub_cer_4573"}, {"rel": "self", "type": "application/geo+json", "title": "21.15107/rcub_cer_4573", "name": "item", "description": "21.15107/rcub_cer_4573", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/21.15107/rcub_cer_4573"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2021-01-01T00:00:00Z"}}, {"id": "3164835394", "type": "Feature", "geometry": null, "properties": {"updated": "2026-04-03T16:28:40Z", "type": "Journal Article", "created": "2021-05-31", "title": "Imaging-based spectrometer-less optofluidic biosensors based on dielectric metasurfaces for detecting extracellular vesicles", "description": "Abstract

Biosensors are indispensable tools for public, global, and personalized healthcare as they provide tests that can be used from early disease detection and treatment monitoring to preventing pandemics. We introduce single-wavelength imaging biosensors capable of reconstructing spectral shift information induced by biomarkers dynamically using an advanced data processing technique based on an optimal linear estimator. Our method achieves superior sensitivity without wavelength scanning or spectroscopy instruments. We engineered diatomic dielectric metasurfaces supporting bound states in the continuum that allows high-quality resonances with accessible near-fields by in-plane symmetry breaking. The large-area metasurface chips are configured as microarrays and integrated with microfluidics on an imaging platform for real-time detection of breast cancer extracellular vesicles encompassing exosomes. The optofluidic system has high sensing performance with nearly 70 1/RIU figure-of-merit enabling detection of on average 0.41 nanoparticle/\uffc2\uffb5m2 and real-time measurements of extracellular vesicles binding from down to 204 femtomolar solutions. Our biosensors provide the robustness of spectrometric approaches while substituting complex instrumentation with a single-wavelength light source and a complementary-metal-oxide-semiconductor camera, paving the way toward miniaturized devices for point-of-care diagnostics.

In this paper, we investigated the effect of humidity on paper substrates and propose a simple and low-cost method for their passivation using ZnO nanoparticles. To this end, we built paper-based microdevices based on an interdigitated electrode (IDE) configuration by means of a mask-less laser patterning method on simple commercial printing papers. Initial resistive measurements indicate that a paper substrate with a porous surface can be used as a cost-effective, sensitive and disposable humidity sensor in the 20% to 70% relative humidity (RH) range. Successive spin-coated layers of ZnO nanoparticles then, control the effect of humidity. Using this approach, the sensors become passive to relative humidity changes, paving the way to the development of ZnO-based gas sensors on paper substrates insensitive to humidity.

", "keywords": ["paper substrate", "disposable sensors", "ZnO nanoparticles", "Chemical technology", "TP1-1185", "02 engineering and technology", "0210 nano-technology", "humidity passivation; paper substrate; ZnO nanoparticles; disposable sensors", "Article", "humidity passivation"]}, "links": [{"href": "http://www.mdpi.com/1424-8220/17/3/516/pdf"}, {"href": "https://doi.org/2592687333"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/Sensors", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "2592687333", "name": "item", "description": "2592687333", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/2592687333"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2017-03-04T00:00:00Z"}}, {"id": "2742380607", "type": "Feature", "geometry": null, "properties": {"updated": "2026-04-03T16:28:09Z", "type": "Journal Article", "created": "2017-08-11", "title": "Fabrication and Characterization of Flexible and Miniaturized Humidity Sensors Using Screen-Printed TiO2 Nanoparticles as Sensitive Layer", "description": "

This paper describes the fabrication and the characterization of an original example of a miniaturized resistive-type humidity sensor, printed on flexible substrate in a large-scale manner. The fabrication process involves laser ablation for the design of interdigitated electrodes on PET (Poly-Ethylene Terephthalate) substrate and a screen-printing process for the deposition of the sensitive material, which is based on TiO2 nanoparticles. The laser ablation process was carefully optimized to obtain micro-scale and well-resolved electrodes on PET substrate. A functional paste based on cellulose was prepared in order to allow the precise screen-printing of the TiO2 nanoparticles as sensing material on the top of the electrodes. The current against voltage (I\u2013V) characteristic of the sensor showed good linearity and potential for low-power operation. The results of a humidity-sensing investigation and mechanical testing showed that the fabricated miniaturized sensors have excellent mechanical stability, sensing characteristics, good repeatability, and relatively fast response/recovery times operating at room temperature.

", "keywords": ["flexible substrate", "Chemical technology", "laser ablation", "humidity sensors", "TP1-1185", "02 engineering and technology", "0210 nano-technology", "TiO2 nanoparticles", "screen-printing", "humidity sensors; flexible substrate; TiO2 nanoparticles; screen-printing; laser ablation", "Article"]}, "links": [{"href": "http://www.mdpi.com/1424-8220/17/8/1854/pdf"}, {"href": "https://doi.org/2742380607"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/Sensors", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "2742380607", "name": "item", "description": "2742380607", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/2742380607"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2017-08-11T00:00:00Z"}}, {"id": "3083211908", "type": "Feature", "geometry": null, "properties": {"updated": "2026-04-03T16:28:31Z", "type": "Journal Article", "created": "2020-09-07", "title": "Biosynthesized iron sulfide nanoparticles by mixed consortia for enhanced extracellular electron transfer in a microbial fuel cell", "description": "The bioanode of mixed consortia was for the first time used to in-situ synthesize iron sulfide nanoparticles in a microbial fuel cell (MFC) over a long-term period (46\u00a0days). These poorly crystalline nanoparticles with an average size of 29.97\u00a0\u00b1\u00a07.1\u00a0nm, comprising of FeS and FeS2, significantly promoted extracellular electron transfer and thus the electricity generation of the MFC. A maximum power density of 519.00\u00a0mW/m2 was obtained from the MFC, which was 1.92 times as high as that of the control. The cell viability was promoted by a small amount of iron sulfide nanoparticles but inhibited by the thick nanoparticle 'shell' covered on the bacterial cells. Some electroactive and sulfur reducing bacteria (eg. Enterobacteriaceae, Desulfovibrio, and Geobacter) were specifically enriched on the anode. This study provides a novel insight for improving the performance of bioelectrochemical systems through in-situ sustainable nanomaterials biofabrication by mixed consortia.", "keywords": ["Electron Transport", "Electricity", "Bioelectric Energy Sources", "Nanoparticles", "Electrons", "Ferrous Compounds", "Electrodes", "01 natural sciences", "7. Clean energy", "0105 earth and related environmental sciences"], "contacts": [{"organization": "Cui, Yan, Chen, Xueru, Pan, Zhengyong, Wang, Yuqi, Xu, Qiang, Bai, Jiaying, Jia, Honghua, Zhou, Jun, Yong, Xiaoyu, Wu, Xiayuan,", "roles": ["creator"]}]}, "links": [{"href": "https://doi.org/3083211908"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/Bioresource%20Technology", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "3083211908", "name": "item", "description": "3083211908", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/3083211908"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2020-12-01T00:00:00Z"}}, {"id": "3113659741", "type": "Feature", "geometry": null, "properties": {"updated": "2026-04-03T16:28:35Z", "type": "Journal Article", "created": "2020-12-21", "title": "Genotype \u00d7 Environment Interaction for Wheat Yield Traits Suitable for Selection in Different Seed Priming Conditions", "description": "

Different seed priming treatments are widely used in order to improve the nutritional status of wheat, as well as to improve its grain yield and yield- related traits. The present study aimed to evaluate the impact of seed priming with zinc oxide nanoparticles (ZnO NPs) on the yield related traits, such as, field emergence, plant height, spike length and grain yield per plant of four winter wheat genotypes (Triticum aestivum L.) during two vegetation seasons of 2018/2019 and 2019/2020. The seeds of each wheat genotypes were primed with different concentrations of ZnO NPs (0 mg L\u22121, 10 mg L\u22121, 100 mg L\u22121 and 1000 mg L\u22121) for 48 h in a dark box by continuous aeration and were sown in soil pots with 60\u201370% moisture content until full maturity. The additive main effects and multiplicative interaction (AMMI) models were used to study the genotype environment effects. The results indicated that the plants response to ZnO nanoparticles significantly increased all of the observed traits of the wheat, while its maximum rates reduced the traits of the wheat. The AMMI analysis revealed the very complex nature of the variation observed in the trial and showed the significant effect of the G\u00d7E interaction, in which the first main component was significant for all components.

", "keywords": ["2. Zero hunger", "0106 biological sciences", "wheat;\u00a0zinc oxide nanoparticles;\u00a0GEI;\u00a0AMMI", "AMMI", "GEI", "Botany", "zinc oxide nanoparticles", "Ammi", "Vegetation", "04 agricultural and veterinary sciences", "15. Life on land", "01 natural sciences", "Article", "Seed priming", "Horticulture", "13. Climate action", "wheat", "QK1-989", "Grain yield", "0401 agriculture", " forestry", " and fisheries", "Multiplicative interaction", "Gene\u2013environment interaction", "Aeration", "Water content"]}, "links": [{"href": "http://www.mdpi.com/2223-7747/9/12/1804/pdf"}, {"href": "https://www.mdpi.com/2223-7747/9/12/1804/pdf"}, {"href": "https://doi.org/3113659741"}, {"rel": "related", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/Plants", "name": "related record", "description": "related record", "type": "application/json"}, {"rel": "self", "type": "application/geo+json", "title": "3113659741", "name": "item", "description": "3113659741", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items/3113659741"}, {"rel": "collection", "type": "application/json", "title": "Collection", "name": "collection", "description": "Collection", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main"}], "time": {"date": "2020-12-19T00:00:00Z"}}], "links": [{"rel": "self", "type": "application/geo+json", "title": "This document as GeoJSON", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items?keywords=nanoparticles&f=json", "hreflang": "en-US"}, {"rel": "alternate", "type": "text/html", "title": "This document as HTML", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items?keywords=nanoparticles&f=html", "hreflang": "en-US"}, {"rel": "collection", "type": "application/json", "title": "Collection URL", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main", "hreflang": "en-US"}, {"type": "application/geo+json", "rel": "first", "title": "items (first)", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items?keywords=nanoparticles&", "hreflang": "en-US"}, {"rel": "next", "type": "application/geo+json", "title": "items (next)", "href": "https://repository.soilwise-he.eu/cat/collections/metadata:main/items?keywords=nanoparticles&offset=50", "hreflang": "en-US"}], "numberMatched": 72, "numberReturned": 50, "distributedFeatures": [], "timeStamp": "2026-04-04T14:24:27.789451Z"}